In contrast to the three American “Covid” vaccines, the version of “Novavax” elicits an immune response with nanoparticles composed of proteins from the surface of the Corona virus that causes Covid-19 disease.
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The Novavax vaccine uses a different technology from the three American vaccines.
The United States has approved its fourth vaccine for use against the Corona virus. The new vaccine from Novavax, a Maryland pharmaceutical company, works differently from the three other Covid vaccines in use.
newspaper said “The New York Times” While it is expected that Novavax doses will play a limited role in the country’s immunization campaign, at least in the beginning, the presence of another approved tool to combat the virus as the mutation continues is a positive development.
Here’s what you need to know about the new vaccine:
technology: In contrast to the three “Covid” vaccines authorized in the United States, the release of “Novavax” elicits an immune response with nanoparticles composed of proteins from the surface of the Corona virus that causes Covid-19 disease. Similar protein vaccines have been used globally for decades.
EffectivenessWith two doses spaced three weeks apart, the vaccine showed an overall efficacy of 90.4 percent, on par with vaccines made by Pfizer and Modern, and higher than that obtained from a single dose of Johnson & Johnson. The Novavax vaccine was 100 percent effective in preventing moderate or severe disease.
Omicron: The vaccine was tested before the omicron mutant appeared, which significantly reduced the effectiveness of other approved vaccines in preventing infection. However, Novavax is developing new versions of its vaccine that target Omicron and its highly infectious sub-mutants. Preliminary data from in vitro and animal studies indicate that a booster dose targeting the BA.1 mutant, which predates the current highly pathogenic version of BA.5, generates robust immune responses to the virus. The company says it expects to get results from a clinical trial of that shot in September, with doses ready in the last three months of the year.
Side effectsThe Novavax vaccine is associated with an increased risk of developing forms of heart inflammation known as myocarditis and pericarditis. The company said it has identified 17 confirmed or probable cases of myocarditis and pericarditis in more than 1 million doses.
The pericardium is a type of serous membrane, a thin-walled sac that surrounds the heart.
The mRNA vaccines from Moderna and Pfizer are also associated with an increased risk of these conditions, but this association did not appear until after they were widely used.
booster dose: Trials have also shown that Novavax works well as a booster dose, and the company is expected to soon seek permission to use it in this way. But the Center for Disease Control and Prevention in the United States has recommended its use as an option for adults as the first vaccination against the Corona virus.
Novavax hopes the vaccine will attract millions of people who have so far refused vaccination, perhaps because they are wary of the technology behind mRNA vaccines.
About 22 percent of people in the United States have not received a single dose of the Covid-19 vaccine.
Transferring it to Arabic at the disposal of: Al-Mayadeen Net