11.29 a.m., February 4th, 2021
British researchers want to test the vaccine effectiveness in a clinical study by combining two different active substances. As the National Institute for Health Research announced that the two vaccines previously approved in Great Britain are to be used by Biontech / Pfizer and Oxford / Astrazeneca be used in a different sequence as the first and second dose.
Further preparations could be added later, it said in the message. The study, which started on Thursday, is said to be more than 800 volunteers in England aged 50 and over and participate about it.
At the same time, the researchers also want to find out how different intervals of four to twelve weeks between giving the two doses. Currently, both vaccines are given in the UK up to twelve weeks apart. More than ten million people in the country have already received a first dose of vaccine, So far, only about 500,000 people have been vaccinated twice.
Given potential bottlenecks in vaccine delivery, it is definitely an advantage To have data that would allow more flexible vaccine distributionUK Government Deputy Chief Medical Advisor Jonathan Van-Tam said. He added: “It is also possible that the combination of vaccines could increase the immune response and produce longer lasting and higher levels of antibodies,” said Van-Tam. That must now be tested.
Russian researchers announced a similar study at the end of last year. A combination of the Russian vaccine should be used “Sputnik V” and the vaccine from the British pharmaceutical company Astrazeneca are used.