British royal men’s hair loss genes are strong, and the probability of genetic baldness in men and women is clear | Life affairs

The powerful hair loss and baldness genes of the British royal family have spared King Charles III, Prince Andrew, Prince Edward, Prince William, Harry, etc. The study pointed out that the source of the royal family’s hair loss came from the Queen’s husband, Prince Philip. In the patrilineal family, he was originally a Greek prince, and his father and grandfather were both bald.

Now the outside world is starting to pay more attention and worry that the hairline of Prince George’s forehead is obviously a little too high. After all, how is the mechanism of hereditary hair loss formed?

Hereditary alopecia is male hormone alopecia, which originates from testosterone in the body under the action of 5α-reductase to form a male hormone DHT (ie dihydrotestosterone, which is the culprit of hair loss), DHT binds to androgen receptors of scalp hair follicle cells After that, the hair follicles will shrink and disappear, and finally form hair loss and baldness.

Existing studies have pointed out that although androgenetic alopecia is “sex hereditary”, there are variables whose genetic expression is affected by gender, that is, males are “dominant” and females are mostly “recessive”. Therefore, hereditary hair loss problem is not only for men.

One article clearly understands the probability of hereditary baldness in men and women, and attaches 3 effective treatments.

Visual inspection can already determine the chance of “genetic hair loss”

First of all, both men and women may inherit the gene for hair loss.

If only one parent is bald, the child will not necessarily be bald. If both parents are bald (or the mother has a hair loss gene but does not show symptoms, that is, recessive inheritance), the son may not escape the ultimate fate of baldness.

Even if the parents are not bald, the son may be bald, because it is possible that the mother carries the hair loss gene, but does not show symptoms (that is, the mother is recessive), and as a male, the son just inherits the mother’s hair loss gene, and unfortunately manifested.

When the hair follicles of men and women have the same sensitivity to DHT, because women have relatively less DHT in their bodies than men, the symptoms and degrees of women will be different from those of men, and the symptoms of women are generally milder than those of men.

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various treatments

Because hereditary hair loss originates from genes, there is still no cure for it in medicine at present, only symptomatic treatment can be given to improve it.

At present, the drugs that have been used for a long time are the oral drug “Finasteride” (Finasteride) and the topical “Minoxidil” (Minoxidil), both of which need to be treated in the early stage of hair loss. Has atrophied and disappeared, it is difficult to work, and both require long-term medication.

“Finasteride” is a doctor-prescribed drug in Hong Kong. It is recommended for men only. The usual dose for the treatment of hair loss is 1mg per day for at least 3 months. Common side effects include dizziness, tiredness, and changes in sexual performance or interest (which are generally less likely to affect sexual performance), and should be discontinued by family planners to avoid the risk of teratogenicity.

After stopping taking “finasteride”, the effect can be reversed within 12 months. It is recommended not to stop the drug suddenly, but to stop the drug gradually, such as taking one tablet a day, changing to half a tablet a day, or taking it once every two days, etc., and so on. Take 3 to 4 months to complete the withdrawal. Before stopping the drug, if minoxidil is not used, it is recommended to apply minoxidil externally.

Topical minoxidil, a vasodilator used to treat hair loss, works by increasing blood flow to hair cells, thereby stimulating their growth. Both men and women can use it, divided into 2% and 5% doses. The appropriate dose should be selected according to the needs and the doctor’s recommendation. This medicine is an over-the-counter medicine in Hong Kong. Common side effects are hair texture changes, itching, contact dermatitis and redness. If the above conditions occur, the dosage and frequency can be adjusted to relieve symptoms. It must be used for a long time, and once the drug is stopped, hair loss will occur again.

If the scalp has not enough hair????, you can consider a hair transplant surgery. Generally, the hair follicles are removed by surgery in the “back-occipital area” of the head. Because the hair in this area is not sensitive to DHT, it is suitable to be transplanted to the hair loss area. It is still necessary to continue the medication to help maintain the effect.

Regular hair transplant surgery, the surgery is successful and the survival rate of hair transplant can reach more than 90%, which generally lasts for 10 to 20 years. However, how long it can last depends on the basic condition of the individual’s hair.

The simplest alternative is to wear a wig.

One article clearly understands the probability of hereditary baldness in men and women, and attaches 3 effective treatments.

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