Berlin – At the beginning of the corona pandemic more than a year and a half ago, there was already the assumption that previous colds with other coronaviruses could lead to a better immune reaction against Sars-CoV-2. One speaks of a so-called cross immunity. In modeling in March 2020, researchers calculated a proportion of zero to more than 30 percent of the population who could be more or less protected as a result.
Charité researchers reported back in summer 2020 in the journal Naturethat “cross-reacting” T cells against SARS-CoV-2 were found in 35 percent of the samples from healthy blood donors, even though the donors never had contact with the virus. These T cells likely came “from previous encounters with endemic coronaviruses,” the researchers wrote. The term “endemic” means that they have been regionally native for a long time.
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