Corona detection in 30 minutes regardless of KIST mutation

KIST “Corona detection in 30 minutes regardless of mutation”

Dr. Lee Kwan-hee’s research team “The sensitivity is comparable to the PCR test”

(Seoul = Yonhap News) Reporter Sujin Oh = A Korean research team has succeeded in developing a diagnostic platform that can determine the presence or absence of the new coronavirus infection (COVID-19) in 30 minutes regardless of mutation.

The Korea Institute of Science and Technology (KIST) is a biomaterials research center where a research team including Senior Researcher Lee Kwan-hee, Senior Researcher Kim Ho-jun, and Postdoctoral Researcher Park Seong-wook is able to detect the Corona 19 virus within 30 minutes with a sensitivity comparable to that of the gene amplification (PCR) method. It announced on the 26th that it has developed a biosensor platform.

The PCR test currently used for the official confirmation of COVID-19 takes several hours to diagnose. Although the simple test kit provides quick results, the detection sensitivity is low and there is a limit to the accurate detection of mutated viruses.

Dr. Kwanhee Lee’s research team used ‘Angiotensin Converting Enzyme 2’ (ACE2), which is used by the Corona 19 virus when it penetrates the human body, to detect not only the existing Corona 19 virus but also the mutated Corona 19 virus.

They manufactured an electrical signal-based semiconductor biosensor platform coupled with an ACE2 receptor, and then optimized the biosensor platform by synthesizing an artificial virus that mimics the physical characteristics of coronavirus.

They explained, “As a result of diagnosis with the developed biosensor platform, we succeeded in real-time detection of the actual coronavirus and various synthesized mutated viruses at the test site within 30 minutes with the sensitivity of PCR test.”

“We plan to commercialize the sensor after standardization and standardization in the near future,” said Dr. Lee. “It is expected to contribute to the establishment of an infection prevention system and social safety net.”

The results of this study were published in the latest issue of ‘Nano Letters’, a journal in the field of nanotechnology.

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