COVID-19: Is Testosterone Deficiency at Risk for a More Severe COVID-19 Course?
Low testosterone increases the chances of getting COVID-19 infection.
Do hormones play a role in causing COVID-19? An American study team has now found proof of this. Men with low testosterone levels in particular seem to have a higher risk of severe COVID-19 courses.
Low testosterone levels in the blood of men are linked to an increased risk of severe COVID-19 courses, according to researchers at the Washington University School of Medicine in St. Louis, USA. The research results were recently published in the JAMA Network Open magazine.
Is there a link between testosterone and gender-specific COVID-19 risk?
Throughout the epidemic, it was clear that men, on average, were more affected by COVID-19 than women. There has been a lot of debate about whether hormone differences are responsible for the gender risk. It was originally believed that elevated levels of testosterone in the blood increased the likelihood of developing severe COVID-19. The current study, however, shows that the opposite could be the case.
The researchers discovered evidence that low blood testosterone levels are linked to more severe COVID-19 disease. However, low testosterone was not found to be a cause of severe COVID-19 illness in the study. On the other hand, low testosterone appears to be a predictor of severe COVID-19 courses in men.
Role of testosterone in COVID-19 unclear.
“During the pandemic, the prevailing perception was that testosterone was bad,” explains study author and professor of medicine Abhinav Diwan. However, the latest results suggest that the opposite is more likely the case for men. According to the study, men were at an increased risk of major COVID-19 events if they had low testosterone levels when they were admitted to the hospital, compared to men with more circulating testosterone in their blood.
What was examined.
The researchers measured hormones in blood samples from 90 men and 62 women admitted to the Barnes-Jewish Hospital for SARS-CoV-2 infection. The hormone levels were determined on the third, seventh, 14th and 28th day of hospitalization. In addition to testosterone, the researchers also measured levels of estradiol, a form of endogenous estrogen, and IGF-1, a growth hormone similar to insulin, a. Bulgarian Business Journal Newsflash.