‘Doctor Yong’ reveals 20 things you should know about the Covid-19 vaccine
On November 7, Prof. Dr. Yong Phuworawan, head of the Center specializes in clinical virology. Department of Pediatrics Faculty of Medicine Chulalongkorn University Post a message through the Facebook page “Yong Poovorawanstating that “Covid-19 vaccine, 20 general things to know (continued from yesterday)
1. All vaccines approved by the World Health Organization. Stimulates immunity well.
2. There is no vaccine that can prevent infection for sure. If infected, the number of infections will be less than those who have not been vaccinated and can reduce the severity of the disease, reduce symptoms, reduce morbidity and death.
3. Immunity and efficiency It decreases over time. In general, high immunity lasts longer than low immunity. Although highly immunogenic vaccines, such as mRNA, are recommended after 6 months of vaccination, especially for high-risk groups, the elderly, and those with immunocompromise.
4. The effectiveness of vaccines depends on many components. study in england High immunity is associated with disease prevention efficacy.
5. Primary immunization: Two doses are used, usually 3-4 weeks apart from each vaccine. Astra Zeneca is 4-12 weeks apart, except for Johnson & Johnson’s one dose.
6. According to the principles of vaccines spacing Between the 1st and 2nd needles, it stimulates higher immunity. (But if the distance is too far to be afraid that there will be an infection first), so if the 2nd needle can’t be injected as scheduled, move the 2nd needle out, not move it in, and it’s too late, even if it’s been a month. No new vaccines have been initiated.
7. Two doses that are in close proximity to each other, as today are considered primary, require a booster, eg hepatitis B injections 0, 1 and 6 months, so it is not uncommon for immunity to be sustained. High and long, requires 3 needle stimulation.
8. Immunity caused by infection will be lower than the immunity arising from the 2 injections
9. Those who have been infected Giving an additional dose of vaccine It will stimulate the immunity to be much higher. Like infection is the 1st vaccination and vaccination is the 2nd dose.
10. Those who have completed 2 vaccinations and are infected, the infection will be like a 3rd dose vaccination or stimulate the immune system will increase a lot. enough to stay long
11. Give a lethal vaccine. a whole virus This is a good initial dose, simulating the body as an asymptomatic infection. And the second vaccination of different types will have a high immunity.
12. Alternating the use of dead yeast and followed by vector viruses such as Sinovac, the first dose, AstraZeneca, the second dose that Thailand provides in limited vaccine conditions. Stimulates immunity well. Similarly, a lethal vaccination followed by 2 mRNA doses boosted immunity similar to that of two mRNA doses.
13. After receiving 2 doses of inactivated vaccination, 3 injections with dead bacteria after 3 months or more will increase the immunity by about 10 times. If stimulated with vector virus or mRNA, it will stimulate very high or 100 times higher.
14. Practical or General There is no need for a post-injection immunity test. will use research study data and issued as a guideline For example, the duration of stimulation of the 3 needles of the vaccine used to stimulate the 3 needles.
15. Those who have received needle 3 stimulation, needle 4 is not stimulated to be much higher, so needle 4 is not necessary, except for those who want to travel abroad. Conditional vaccination is required. of that country
16. Currently available vaccines do not protect against infection. Therefore, group immunity cannot be used to prevent disease outbreaks. can help reduce the severity of the disease And the population should be vaccinated as much as possible.
17. Existing vaccines should be administered as quickly as possible. should not be stored in the refrigerator To keep the second needle, the second needle can be moved out. in case of shortage Otherwise, some vaccines are short-lived, such as mRNA. Vaccines last up to 1 month after thawing. Elderly risk group should be vaccinated first And then it comes down to those who are at risk. less risk of disease to reduce morbidity and mortality
18. If there are thousands of patients a day But there are very few deaths. For example, 2-3 people per day would have to agree and next, everyone has a certain level of landscape. The disease will be less severe. like a common respiratory disease
19. This virus can mutate over time. But the mutation to the coronavirus vaccine is not the same as the flu. Changes in vaccine types occur much later than influenza. If the stimulation of the immune system is very high It will reduce the severity of the delta species.
20. The balance that every life needs to live In the epidemic of disease, both physical and mental health, including economic conditions Everyone must cooperate and know how to share. Tomorrow will definitely be better than today.