Early diagnosis of Alzheimer’s disease through blood test

Alzheimer’s – Swedish and British scientists say they have developed a method for predicting Alzheimer’s. With the help of blood analyzes, the disease can be recognized years before the first symptoms appear, they write in “Nature Aging”.

Although the background to Alzheimer’s is not fully understood, experts believe that the disease is triggered by an accumulation of proteins in the brain. It is believed that these contribute to the destruction of nerve cells. Some of these proteins can be found in the blood.

Based on this finding, the scientists developed a model with which they want to predict the risk of developing Alzheimer’s disease. To do this, they evaluated blood samples from more than 550 patients with mild cognitive impairments. In 88 percent of the cases, a correct prediction of the possible occurrence of Alzheimer’s disease was apparently possible within a period of four years.

Experts described the method as a possible breakthrough in the fight against dementia. Oxford University neurology professor Musaid Husain said Monday the study could be an important step “towards an earlier diagnosis, as well as testing new therapies in earlier stages of the disease”.

Around 50 million people worldwide suffer from Alzheimer’s, the most common form of dementia. The disease gradually destroys brain tissue and steals memories from those affected.

Specialized publication number https://doi.org/10.1038/s41467-020-19737-2

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