It seems that the suffering of the search for products and treatments to prevent hair loss is on its way to end, after a new study made an important discovery about the cells responsible for the growth of hair follicles that may help in hair loss. Baldness cure in the future.
A team of scientists has made a pivotal discovery about the behavior of master cells in the follicle, and has identified a previously unknown role for a signaling molecule for stem cells important for hair growth, according to a study published in “New Atlas.”
The cells that the study focused on are known as dermal papillary cells, or dermis papillary, which are located in the hair follicle and help determine the speed, thickness and length of hair growth, which made it the focus of many efforts to develop new treatments for hair loss.
It has also been focused on research and studies aimed at explaining how it can be produced from stem cells or 3D-printed copies of them, for example, many of which have raised some promising possibilities.
The role of the SCUBE3 molecule
As part of an effort by a team of scientists at the University of California to search for new treatments for androgenetic alopecia, or male pattern baldness, lab mice were modeled with hyperactive dermal papillary cells, which led to excessive hair growth.
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By observing how papillary cells activate signaling molecules, the scientists were able to come up with what is considered a new key to hair growth. They discovered the previously unknown role of a molecule called SCUBE3, which was then validated through experiments with human follicles.
split start
In turn, researcher Maxim Plekus said that “at different times during the life cycle of a hair follicle, the same dermal papilla cells can send signals to either keep the follicles dormant or lead to new hair growth.”
He explained that he and his research team discovered “that the signaling molecule SCUBE3, which is naturally produced by dermal papillary cells, is the transmission medium used to tell neighboring hair stem cells to begin dividing, which heralds the start of new hair growth.”
Patented
In another round of experiments, the scientists injected the SCUBE3 molecule into mouse skin by culturing human scalp follicles.
The procedure actually stimulated strong hair growth, both in dormant human follicles and in mouse follicles that surround them.
Expressive – iStock
Scientists believe that the new results provide promising evidence before clinical tests that SCUBE3 or similar molecules can be used as a hair loss treatment, and they have submitted a provisional patent application for this purpose.