The doctor recommends that if you have doubts about the use of drugs, it is best to consult a doctor. (Picture taken from freepik)
[Health Channel/Comprehensive Report]Taiwan introduced Paxlovid, an anti-Wuhan pneumonia (new coronavirus disease, COVID-19) drug, but the government announced too many taboos, which made people at a loss, and most of them were heart disease patients. Cardiologist at Yuping Clinic Liu Zhongping’s Facebook page “Cardiology Notes from Dr. Zhongping Liu” issued a document to sort out a list of heart-related drugs that “can” and “can’t” be used together, and said that the mortality rate of heart disease patients after diagnosis is more than 2 to 3 times higher than that of the general population, so more immediate drug treatment is needed, and it is recommended that When in doubt, it is best to consult a doctor.
Drugs that should never be used together
Antiarrhythmic drugs:amiodarone 、 dronedarone 、 flecainide 、 propafenone 、 quinidine
Please read on…
Lipid drugs:lovastatin、simvastatin
Liu Zhongping suggested that if the problem of arrhythmia is in a stable state, other drugs can be considered instead. Because the blood lipid drug is a long-term chronic prevention, it can be directly suspended for five days, the antiviral drugs are finished, and the original arrhythmia and blood fat drugs can be restored.
Drugs that can be used in combination but must be closely monitored
Anticoagulant drugs:warfarin 、 rivaroxaban 、 dabigatran 、 apixaban 、 edoxaban 等
Blood pressure medicine:Calcium blockers: amlodipine, diltiazem, felodipine, nicardipine, nifedipine
Because of the risk of bleeding with anticoagulant drugs, it is recommended to closely monitor the blood coagulation function or reduce the use of anticoagulant drugs. If it is not a high-risk group with a heart metal valve or a recent stroke, the doctor assesses that the chance of embolism within 5 days is not high. If so, Liu Zhongping suggested to use antiviral drugs as the mainstay.
In addition, only the above-mentioned calcium ion blockers of blood pressure drugs will interact with Paxlovid, which may reduce blood pressure and heartbeat. However, as long as the dose of calcium ion blockers is appropriately reduced by frequent measurement, Liu Zhongping believes that antiviral drugs can interact with Paxlovid. Combined use of calcium ion drugs. Please take other blood pressure medicines as usual, but you should measure and observe more, and pay attention to whether there are side effects of dizziness.
Aspirin, which is most commonly used by heart patients, does not interact with Paxlovid and can be used simultaneously. Another well-known antiplatelet drug, Plavix, may be less effective due to Paxlovid; other antiplatelet drugs may also be affected by antiviral drugs. However, there may be immediate danger due to cardiovascular embolism. If you want to use antiviral drugs, you must consult a cardiologist first. If you have just placed a vascular stent within a year, Liu Zhongping recommends that you try to use antiplatelet drugs as much as possible. If necessary Choose other antiviral drugs, such as monapiravir (Molnupiravir), etc.
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