Korean researchers develop medical nanoparticles that reach cancer cells without accumulating in the liver

A technology has been developed that can deliver drugs to specific parts of the body without accumulating in the liver, the Digital Times reported. The Korea Atomic Energy Research Institute (KAERI) announced on the 13th that a research team led by Dr. Jung-Hoon Park and his research team has developed ‘medical iron nanoparticles’ that reach cancer cells without accumulating in the liver using a cyclotron (particle accelerator). The research team stably bound ‘zirconium-89 (a radioactive isotope used for imaging diagnostics)’, a diagnostic isotope, into iron nanoparticles with a size of 100 to 200 nanometers, and then coated them with a polymer to neutralize the surface charge. In particular, the nanoparticles are made neutral rather than negatively or positively charged, so binding to serum proteins is reduced.

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