Krill Oil Supplements May Promote Healthy Aging – Medical Practice

Krill oil appears to protect the brain from age-related diseases

With krill is largely made from Antarctic mini-crustaceans (krill). Similar to fish, krill is rich in Omega-3 fatty acids. It also contains krill oil Cholinean elementary cell building block, as well as the powerful antioxidant Astaxanthin. In a recent study, a research team from Norway now suggests that krill oil Brain before age-related diseases protects.

researchers of University of Osloof the Oslo University Hospital as well as des Akershus University Hospital have found that krill oil Neurons before altersbedingter Degeneration protects and in brain cells of several Signs of aging suppressed. The research results were recently published in the renowned journal “Aging” presented.

In some regions, people are living longer

In previous studies, there is already a lot of evidence that people in certain regions have an unusual long life to have. In part, this will depend on what is customary in each region nutrition returned. Among other things, such a longevity has been observed, for example, in some Mediterranean regions or in parts of Japan.

Similar diet in long-lived regions

What unites these regions is a similar diet rich in fish and seafood is. These represent an excellent Source of omega-3 fatty acids The long-chain fats have already been a central topic in numerous research projects.

Previous research has suggested that omega-3 rich krill oil has a positive effect on health. However, the Norwegian working group has now been able to elucidate the molecular mechanisms that lead to the positive effects on the brain for the first time.

How does krill oil affect brain cells?

Using nematodes and human cells, the team was able to demonstrate that krill oil has a positive effect on various gene expressions acts that to Attenuation of various age-related characteristics contribute, including

  • oxidative stress (imbalance between free radicals and antioxidants),
  • proteotoxic stress from misfolded proteins,
  • senescence (cessation of cell division),
  • genomic instability,
  • mitochondrial dysfunction.

In addition, the researchers were able to prove that krill oil anti-inflammatory effect on brain cells as it increases neuronal resilience, which promotes health-regulating transcription factors (such as SNK-1).

Krill oil had a particularly positive effect on the so-called dopaminergic neurons out. These are nerve cells in the brain that are responsible for the production of Dopamine are responsible. Dopamine, in turn, is a chemical messenger involved in many important biological processes, including movement, motivation, and cognition.

The effect cannot be attributed to Omega 3 alone

The researchers emphasize that the effect is due to several substances contained in krill oil. In addition to omega 3, the oil also contains so-called Choline contain. It is a molecular component for the formation of membranes. In addition, choline is used for the Synthesis of lipoproteins required for the transport of fats through the blood.

Moreover, krill oil contains the strong Antioxidans Astaxanthin. This is a natural dye belonging to the Carotenoids belongs and is responsible for the red color of the oil.

Krill oil appears to promote healthy aging

“In summary, krill oil switches global gene expression programs and promotes healthy aging by reversing multiple aging traits, suggesting further preclinical and clinical investigations.”sum up the scientists involved in the study.

“Thus, krill oil supplementation could serve as a possible approach for interventions for healthy brain aging”comments the working group in conclusion.

Results have yet to be verified in humans

However, the study was conducted on nematodes and on human cells. Whether the effect in humans is actually affected by taking a Dietary supplement with krill oil developed, must first be examined in further studies. In any case, the research results are promising that this could be the case. (vb)

Author and source information

This text corresponds to the requirements of medical specialist literature, medical guidelines and current studies and has been checked by medical professionals.


Graduate editor (FH) Volker Blasek


  • Tanima SenGupta, Yohan Lefol, Lisa Lirussi, et al.: Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging; in: Aging (2022),
  • Aging: Krill oil protects dopaminergic neurons from age-related degeneration (veröffentlicht: 23.11.2022),

Important NOTE:
This article contains general advice only and should not be used for self-diagnosis or treatment. He can not substitute a visit at the doctor.

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