Thursday, January 6, 2022, 10:56 PM.
Professor Dr. Somdet Chaofa Krom Phra Sri Sawangkhawatana Worakatiya Rajanari President of Chulabhorn Research Institute special lecture on cancer oncogenesis for medical students, nurses, public health workers and health science personnel Suranaree University of Technology through electronic media at the Tippiman Palace Nakhon Ratchasima Province
6 January 2022 Time 12. 50 minutes Professor Dr. Somdet Chaofa Krom Phra Sri Sawangkhawatana Worakatiya Rajanari The President of Chulabhorn Research Institute came out at the Throne Hall, Thippiman Palace. Her Royal Highness gave a special lecture on Cancer Oncogenesis, bestowed upon 2nd year medical students, 3rd year nursing students, 1st year public health students, graduate studies and health science personnel. Suranaree University of Technology for the academic year 2021, a total of 104 people through electronic media (online). In this regard, Associate Professor Dr. Anan Thongra-a, President of Suranaree University of Technology Watch and report and express gratitude.
for this course His Highness will give lectures on 7 main topics. which is based on genetics” and the topic “Different Stages of Cancer and Related Mechanisms” which this course is of great importance to medical students. Because cancer is currently the leading cause of death in the country and tends to have an increasing incidence steadily.
In the first topic, His Highness gave an overview of cancer incidence and the biology of cancer cell growth. The incidence of cancer is caused by many factors. both from genetics, environment and lifestyle, including exposure to chemicals He also described the characteristics of cancer cells which are different from normal cells. There is an incessant division of samples. increase the number endlessly The invasion and metastasis to other tissues due to various biomolecular and biochemical changes led to the discovery of a gene that could be a key starting point for cancer called oncogenes. Cancer genes and genes that act against the division and growth of cancer cells. inhibition of cancer cell division control And the development of cancer treatments can be achieved through targeted therapies.
In the second section, Her Royal Highness gave a lecture on the topic “Different Stages of Cancer and Related Mechanisms” on the multistage cancer process, namely initiation, promotion, and metastasis. (Progression), which are all complex in themselves. The initial stage is about the mechanism of chemical cancer. which at this time cannot be fully understood But it is believed that it can be separated into two forms: a mechanism that directly destroys or alters DNA. mutate and later become cancerous cells This is considered the initial stage of the cancer process. But a normal human body can repair DNA. or genes with enzymes before cells divide so it can maintain its original condition which structural abnormalities in this DNA It is the starting point where the process of regulating cell division and function is misunderstood.
His Highness gave an example of the process caused by different types of direct DNA-destroying carcinogens, such as aflatoxin. Aflatoxin is a mycotoxin found in various grains. that are often found in foods such as fermented fish, shrimp paste, certain beverages, etc., and mechanisms that do not directly destroy DNA This mechanism is altered in the system involved in the regulation of gene expression. which leads to cancer which throughout the lecture given today His Highness gave an example to make students understand the content. and lessons are easier And all are grateful to His Majesty’s dedication and preparation for teaching fully. counted as the greatest grace