Nanotech-Mahidol tests ‘Zinc Ion’ ready to be delivered directly to Tropical Medicine Hospital

13 May 2021


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National Nanotechnology Center (Nanotech), National Science and Technology Development Agency (NSTDA.) Together with the Faculty of Tropical Medicine Mahidol University Presenting the results of testing for the efficacy of organic zinc ion antiviral-bacteria disinfectant. After spraying on the surface for 24 hours.

Help to strengthen confidence in safety Reduce staff workload Reduce the cost of using disinfectants for the building site. Answering needs in the era of the epidemic crisis Together with Unisil Group Co., Ltd. deliver virus-bacterial disinfectants to the Hospital for Tropical Medicine.

Assistant professor Dr. Weerapong Bhumirattanapraphin Dean of the Faculty of Tropical Medicine Mahidol University Said The beginning of the Faculty of Tropical Medicine to play a role in this research. That is, while Thailand has an epidemic of disease-causing coronavirus infection. COVID-19 Mahidol University has encouraged the Faculty of Tropical Medicine to consult with the National Science and Technology Development Agency (NSTDA) to find out how to cope with the disease. COVID-19 Mahidol University and NSTDA have signed an agreement for research and development in health and medicine by Dr. Narong Sirilertworakul. Director of the National Science and Technology Development Agency (NSTDA) and Professor Banchong Mahisavariya, President of Mahidol University, signed on 16 July 2563

Under the signing of cooperation at that time The Faculty of Tropical Medicine and NSTDA have conducted several joint research projects. By the strengths of the Faculty of Tropical Medicine Is a medical institution with a research team involved in the diagnosis, treatment and prevention of disease. There is a Tropical Medicine Diagnostic Reference laboratory. or TMDR Which is a network laboratory tested for laboratory expertise For detecting the genetic material of the new corona virus (SARA-CoV-2) In a way Real time RT-PCR From the Department of Medical Sciences Ministry of Public Health There are staff who perform diagnostic tests. Confirm sample specimens from patients, exposed people, and people with a history of infection risk by means of Real time RT-PCR Since the outbreak of the disease

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While the National Nanotechnology Center NSTDA has several research areas that can develop products (Product Development). Especially products used for sterilization Which can prevent the transmission of infectious diseases By the National Center for Nanotechnology And the Faculty of Tropical Medicine Therefore working together strongly Until now, the results have been expanded to test the efficacy of disinfectant after spraying on the surface. Which is a research that can be further developed into a ready-to-use product, namely Organic virus and bacteria disinfectant with organic zinc ion composition. And in addition, the Faculty of Tropical Medicine There is still research being developed in conjunction with Another nano-tech center is also being developed. Negative pressure helmet Therefore, it is a good opportunity that the Faculty of Tropical Medicine and the National Center for Nanotechnology Will cooperate to produce research results To develop further into the product Related to the diagnosis, treatment and prevention of other tropical diseases As well as Neglected Tropical Diseases (NTDs). In the future

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Dr. Wannee Chinsirikul, Director of the National Nanotechnology Center (Nanotech) NSTDA. Said that at present, the overall health and medical research, NSTDA has important goals to support and accelerate the building of research and development capabilities that meet the needs of the country in the public health system, such as innovative drugs, vaccines, biological drugs. And medical equipment Including the development of personnel base and cooperation with partner agencies in this field In the field of clinical research and data management of medical science To effectively build a strong platform for the health of the country Throughout the past period, NSTDA has continuously undertaken research and development. To meet the health needs of the country and Including receiving funding from external sources in collaboration with various universities

“Even a year 2563 Thailand faces the problem of a new coronavirus outbreak or Covid-19 As a result, the country’s public health system has been greatly affected. There is an urgent need for research and development in health and medicine to be applied for both academic and professional purposes. Economy and society As for Nanotech, NSTDA has adjusted the work plan to create a separate project based on the knowledge base and expertise of the research team to meet the needs of the country in the epidemic situation. 2 The work group includes research and development on crisis response. COVID-19 And work on economic recovery after the crisis COVID-19 Such as the coronavirus rapid detection kit for early screening, Filter and mask for protection against dust. PM 2.5 Bacteria and viruses, Negative pressure cap Negative Pressure Helmet Etc. “Dr. Wannee said

During this situation, NSTDA has urged the results of research on health and medicine to be utilized. With the establishment ofTechnical and Technical Committee for Supporting the Epidemic Situation of the Coronavirus Disease 2019 (COVID-19) And the research on the development of disinfectants with zinc ions developed. Which has properties that can stay on the surface for a long time It also can prevent various infections for a longer time. Which should result in protocol Cleaning in various hospitals Change Without frequent cleaning, the committee therefore proposed a zinc ion disinfectant to be tested at the Faculty of Tropical Medicine. Mahidol University

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Which is a partnered university with NSTDA which has expertise in basic medical science and applied medical science In tropical medicine As well as expertise in antimicrobial activity testing That is the origin of Project to test the performance of organic zinc ion disinfectant after spraying on the surface That received support from Department of Microbiology and Immunology Faculty of Tropical Medicine Mahidol University

From the research project “Development of zinc ion production process for inhibiting bacteria” by Dr. Warayut Sajomsaeng Nanotechnology Research Team Nanotech Compound Materials and Coatings Research Group Which is a sub-project under the Target Strategic Integrated Plan (Spearhead) Together with the National Center for Genetic Engineering and Biotechnology (Biotech) NSTDA, using nanotechnology to stabilize zinc ions and increase the efficiency of bacteria and viruses quickly. And long-lasting It is different from the products available in the market. With a high level of virus killing efficiency

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The results of laboratory tests * showed that it can kill the virus inside. 1 Minutes equivalent to products imported from abroad At an accessible price Equivalent to products available in the market. The disinfection performance of the medium is odorless and non-flammable, as well as passing the skin irritation test from the Institute. Aisa dermscan By testing with volunteers Including the test Toxicology and Bio Evaluation Service Center (TBES) The Toxicology and Biological Testing Service Center NSTDA found that it is safe and does not irritate.

* Virus killing efficiency test results, such as H1N1, H5N1, Coronavirus e.g. SARS, MERS, Porcine epidemic diarrhea virus (PEDV) (Coronaviridae) and SARS-CoV-2 (Covid-19) Etc. Unicil Group Company Limited, a private technology transfer recipient Sent for testing from reliable institutions such as Blutest Laboratory From england

Cooperation between Nanotech NSTDA and Department of Microbiology and Immunology Faculty of Tropical Medicine Mahidol University by Assoc. Prof. Dr. Yellow Head of Department of Microbiology and Immunology In the performance testing project, the disinfectant contains organic zinc ions after spraying on the surface. Since at present there is no method for testing the efficiency of disinfectant after spraying to use on the surface for how long it is still effective for sterilization. And how often must be re-sprayed on the surface in order for the disinfectant to remain effective? The cation of organic zinc ions at nanometer scale and are highly stable can be dispersed in a film coating on the surface and still have long-lasting sterilization performance.

From the performance test of an organic zinc ion disinfectant. Can maintain the efficiency of killing bacteria 100% After spraying on the surface for a long time 24 Hour by bacteria used for testing are Salmonella Choleraesuis, Staphylococcus aureus and Pseudomonas aeruginosa And can maintain the efficiency of killing the virus Porcine epidemic diarrhea virus (PEDV) Which is a family virus (Coronavirus) As well as yeast SARS-CoV-2 After spraying on the surface for a long time 24 hour

Currently, Nanotech NSTDA is in the process of coordinating with Thammasat Hospital. And field hospitals under the Ministry of Higher Education, Science, Research and Innovation (OWN) for use in disinfecting risk areas. With great support from Unicil Group Co., Ltd. who has received technology transfer and research from Nanotech NSTDA.

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