Natural immunity from coronavirus compared with vaccination

Experts believe that the vaccine is still better: “Protects against the risk of serious illness or death.”

Natural COVID-19 infections trigger a stronger secondary immune response than the vaccine, according to new research. Natural infection causes the body to produce memory B cells that become stronger. These cells develop and produce antibodies that work against new strains of coronavirus.

Natural COVID infection triggers a stronger secondary immune response than the vaccine.

As writes Daily Mail, important components of the body’s immune response, called memory B cells, continue to develop and become stronger for at least several months, producing powerful antibodies that can neutralize new variants of the virus.

In comparison, vaccine-induced memory B cells are less resistant, develop for only a few weeks, and never “learn” to defend against variants.

COVID vaccines induce more antibodies than the immune system after coronavirus infection. But the immune system’s response to infection appears to be superior to its response to vaccines when it comes to memory B cells.

If the effect is replicated in children who are unlikely to develop symptoms of COVID, it will increase the likelihood that they may be better protected by natural immunity than vaccination.

Regardless of whether antibodies are induced by an infection or a vaccine, in many people their levels drop within six months. But memory B cells are ready to make new antibodies if the body encounters a virus.

Prior to this study, there was little data on how vaccine-induced B cells compare to infection-induced B cells. The researchers warn that the benefits of stronger memory B cells after infection do not outweigh the risks associated with the coronavirus.

“While a natural infection can cause antibodies to mature with broader activity than a vaccine, a natural infection can also kill you,” said study leader Michel Nussenzweig of Rockefeller University. “The vaccine will not do this and, in fact, protects against the risk of serious illness or death from infection.”

Earlier, another study found that the Delta variant of the coronavirus does not cause more serious illnesses in children than earlier forms of the virus.

The researchers lacked information on differences between groups that might have influenced the results, such as whether restrictions were imposed and the effects of different seasons.

“Our data shows that the clinical characteristics of COVID due to Delta variant in children are broadly similar to COVID associated with other variants,” the researchers concluded.

This observation correlates with data provided by the US Centers for Disease Control and Prevention (CDC). “While we are seeing more cases in children, these studies have shown that there was no increase in the severity of the disease in children,” CDC director Dr. Rochelle Walenski said in a statement about the Delta wave of infections.


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