Ozempic Face: How to Avoid It

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Combating ‘Ozempic Face’: How to maintain a Youthful Look during Weight Loss

April 28, 2025

The rapid rise in popularity of GLP-1 receptor agonists like Ozempic and wegovy for weight loss has brought about a new concern: “Ozempic face.” This term, circulating widely on social media, describes the gaunt or aged appearance some individuals experience due to facial fat loss and skin sagging after significant weight loss. But can this side effect be avoided? According to Dr. Rocio Salas-Whalen,a U.S.-based endocrinologist and obesity specialist, the key lies in maintaining adequate protein intake during the weight loss journey.

In an April 17 episode of The Mel Robbins Podcast,Dr.Salas-Whalen addressed the concerns surrounding “Ozempic face,” clarifying that, “Well, it is not the GLP-1 (that changes the appearance of someone’s face). It is the rapid weight loss or significant weight loss. And why is this? Because of not eating enough protein.”

Dr. Rocio Salas-Whalen explains the link between protein intake and “Ozempic face” on The Mel Robbins Podcast.

The Science Behind “Ozempic Face”

Ozempic (semaglutide) is a medication primarily prescribed for managing type 2 diabetes. It mimics the effects of the GLP-1 hormone, which helps regulate blood sugar levels and also slows down gastric emptying, leading to reduced appetite and subsequent weight loss. While the drug itself doesn’t directly cause facial changes, the rapid weight loss it facilitates can impact facial structure.

Facial fat provides volume and support to the skin. When weight is lost quickly, this fat diminishes, potentially causing the skin to sag and wrinkles to become more prominent. This effect is compounded if muscle mass is also lost, further reducing the face’s underlying support structure.

Did you know? The average adult loses between 0.5% and 1% of their muscle mass each year after age 30. Rapid weight loss can accelerate this process if not managed properly.

Protein: The Key to Prevention

Dr. Salas-Whalen emphasizes the crucial role of protein in mitigating “Ozempic face.” She explains, “So, if you are losing muscle because you don’t have enough protein in your diet while on this (GLP-1) medication, you are not only going to lose muscle, you are going to lose hair.You are going to lose the elasticity in your skin because you need protein to make collagen and elastin. Also,you need muscle to fill the gaps of the fat loss. The goal here is not (to be) skinny – it is strong and fit.so, you need to fill those pockets with muscle. Now, if you are not losing muscle by increasing your protein intake, then you are going to make enough collagen. You are losing weight slowly, so you are allowing you are allowing your skin to adapt to the changes. But if you lose weight rapidly, it means that you are also losing muscle, you don’t have enough protein in your diet, you are not making collagen and elastin.”

Protein is essential for building and repairing tissues,including muscle and collagen. Collagen is the most abundant protein in the body and provides structure and elasticity to the skin.

A 2023 study published in the Journal of the American Academy of Dermatology found that individuals with higher protein intake experienced less skin sagging after significant weight loss compared to those with lower protein intake.

beyond Protein: A Holistic Approach

While adequate protein intake is paramount, a holistic approach to weight loss is essential for maintaining a youthful appearance. This includes:

• Slower weight loss: Aim for a gradual weight loss of 1-2 pounds per week to allow the skin to adapt.
• Strength training: Incorporate resistance exercises to build and maintain muscle mass, which helps fill out the face and prevent sagging.
• Hydration: Drink plenty of water to keep the skin hydrated and plump.
• Healthy fats: Consume healthy fats like those found in avocados, nuts, and olive oil, which contribute to skin elasticity.
• Skincare: Use a good quality moisturizer and consider incorporating products with ingredients like retinol and vitamin C, which can boost collagen production.

Addressing the Counterargument: Genetics and Aging

while lifestyle factors play a significant role in facial aging during weight loss, it’s crucial to acknowledge the influence of genetics and the natural aging process.Some individuals are genetically predisposed to thinner skin or a faster decline in collagen production. Additionally, as we age, our skin naturally loses elasticity, making it more susceptible to sagging, regardless of weight loss.

Thus, while a high-protein diet, strength training, and other preventative measures can considerably mitigate “Ozempic face,” they may not completely eliminate it for everyone. Consulting with a dermatologist or plastic surgeon can provide personalized recommendations for addressing age-related skin changes.

Real-World Examples

Consider the case of Sarah J., a 45-year-old woman who lost 60 pounds in six months using Wegovy. Initially, she was thrilled with her weight loss but became concerned about the gaunt appearance of her face. After consulting with a registered dietitian, she increased her protein intake to 1 gram per pound of body weight and started a strength training program. Over the next few months, she noticed a significant betterment in her facial appearance, with less sagging and a more youthful look.

Another example is Michael B., a 52-year-old man who experienced significant facial fat loss after losing 80 pounds with Ozempic. He opted for hyaluronic acid fillers to restore volume to his face.While fillers can provide temporary relief, Dr. Salas-Whalen emphasizes that addressing the underlying issues of muscle and collagen loss through diet and exercise is a more enduring long-term solution.

Pro tip: Consult with a registered dietitian or certified personal trainer to create a personalized plan that addresses your specific needs and goals.

The Importance of a Balanced Perspective

It’s critically important to remember that weight loss, especially when medically assisted, is a personal journey with both physical and emotional aspects.While “Ozempic face” is a valid concern, it shouldn’t overshadow the significant health benefits that GLP-1 medications can provide for individuals struggling with obesity and type 2 diabetes. By adopting a proactive and balanced approach, individuals can minimize potential side effects and achieve their weight loss goals while maintaining a healthy and youthful appearance.

FAQ

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Combating ‘Ozempic Face’: Expert Insights from Dr. Anya Sharma

Archyde News recently sat down with Dr. Anya Sharma, a board-certified cosmetic dermatologist renowned for her expertise in facial rejuvenation and anti-aging treatments, to discuss the growing concern of “Ozempic face” and how to maintain a youthful appearance during weight loss.

understanding the Phenomenon: What Exactly is ‘Ozempic Face’?

Archyde News: Dr. Sharma, can you explain exactly what “Ozempic face” is and why it’s become such a hot topic, especially with the increasing usage of medications like Ozempic and Wegovy?

Dr. Sharma: Certainly. “Ozempic face” is essentially a term used to describe the changes people are seeing in their facial appearance, particularly after important weight loss facilitated by GLP-1 receptor agonists. The rapid loss of facial fat,coupled with potential loss of muscle mass,can lead to a gaunt look,sagging skin,and more pronounced wrinkles. It’s not necessarily the medication itself causing this, but rather the speed and magnitude of the weight loss.

Protein and beyond: The Keys to Prevention

Archyde News: The article mentions protein intake as a key factor. How crucial is protein, and what other lifestyle adjustments are crucial to counteract these effects?

Dr. Sharma: Protein is absolutely critical. It’s the building block for muscle, and it’s essential for collagen and elastin production—the components that give our skin its plumpness and elasticity. Without enough protein, you’re losing muscle along with fat, intensifying the gaunt appearance. Beyond protein, a slower rate of weight loss is incredibly important, along with incorporating focused strength training, staying well-hydrated, consuming healthy fats, and establishing an appropriate skincare routine.

Beyond the Basics: Advanced Skincare and Treatments

archyde News: What role do skincare and cosmetic treatments play in maintaining a youthful appearance while undergoing weight loss? Are there specific ingredients or procedures you recommend?

Dr.Sharma: Absolutely. A good skincare routine is essential, including a high-quality moisturizer and products containing retinol and vitamin C to stimulate collagen production. In terms of treatments, we can consider options such as hyaluronic acid fillers to restore volume—though the effectiveness isn’t as enduring as the other methods. Also, non-invasive procedures like radiofrequency or ultrasound treatments can definitely help tighten the skin and stimulate collagen. Though,these are best used to assist and enhance,not replace the core focus on lifestyle adaptations.

Genetics, Aging, and Realistic Expectations

Archyde News: How much do genetics and natural aging play a role? Can preventative measures fully eliminate these effects for everyone?

Dr. Sharma: Genetics and the natural aging process undeniably influence changes in facial appearance. Some individuals may be predisposed to factors such as thinner skin or less efficient collagen production,perhaps making them more susceptible to changes. While preventative measures can certainly mitigate “Ozempic face,” they may not eliminate it entirely. A holistic strategy offers the most potential, but its very critically important to maintain some realistic expectations. Seeking professional advice from a dermatologist can also provide personalized recommendations based on individual needs.

A Thought-Provoking Question

archyde News: Dr. Sharma,what is the biggest change you’ve seen in your patients’ approach to weight loss due to the popularity of these medications? And,relatedly,What one piece of advice do you have for anyone currently using or considering using weight-loss medication to avoid “Ozempic face”?

Dr.Sharma: “I’ve seen a big shift toward a more complete, informed approach to weight loss. Patients are moving beyond simply focusing on the scale and are much more interested in optimizing their overall health and appearance. I’d advise anyone using or considering these medications is to make sure they have a strong support system in place. This includes a medical professional who can monitor your health as well as a nutritionist and/or certified personal trainer. With a holistic strategy in place,you’ll be well-positioned to manage weight loss side effects.”