Precision medicine would replace traditional treatments vs. cancer

In the words of the INCan specialist, there is a faster response than with chemotherapy and there are fewer side effects

  • ADRIÁN AGUIRRE
  • 05/08/2020
  • 13:57 hrs.

What happens when all the people with Cancer Are they treated with the same therapy? Should all patients be treated with the same treatments? According to the specialist from the National Cancer Institute (INCan), Omar Macedo, there is a way that people with Cancer be better cared for and one of the possible cancer treatments is the targeted therapy o personalized therapy.

During the webinar “Precision Medicine and Cancer“organized by the Mexican Association for the Fight against Cancer AC, Dr. Macedo mentioned that the personalized treatment guarantees better results, as the type of Cancer that the person has and can be given care that is according to their needs.

What is the targeted therapy? Here we explain it

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Precision medicine: one of the possible cancer treatments

Dr. Macedo revealed that the “traditional” view of treatment against Cancer is to treat patients with the same therapy, but that could have several scenarios:

“For some it will take effect, others will have no effect and some others will present a level of toxicity,” explained the specialist, who stressed that treatments do not always work.

“The same treatment for each group of diseases is not the best option, since patients may respond differently to the same medicine: antidepressants and asthma medications, for example, have a 38% probability of failure, diabetes medications have a 43% chance of failure, arthritis 50%, Alzheimer’s 70% and Cancer 75% “, explained Dr. Macedo in his presentation.

Under this scheme, Macedo mentioned that precision medicine is more exact in that sense, since from the same treatment for all, a stratification is made where people are grouped by disease, subtypes, demography, clinical aspects and biomarkers; then there is precision medicine, where an individual patient is personalized and their preferences, clinical aspects, medication history, environment, behaviors and habits and biomarkers are evaluated, making “precision medicine” be just that, precise treatment.

Photo: webinar screenshot “Precision Medicine and Cancer

For personalized medicine, molecular tests are performed on patients with Cancer and with this, it is determined which treatment is for each person, which results in higher levels of effect, compared to the traditional approach.

“The traditional approach is no longer recommended. The personalized one is better. An adequate biopsy allows adequate treatment. The process is that the patient arrives with the doctor, studies are carried out, a sample of the tumor tissue is taken (biopsy) and This is sent for revision to pathology where the tumor is named, hence the specific molecular tests are requested, these molecular tests are performed with RT-PCR (polymerase chain reaction with reverse transcriptase) or a sequencing of the following generation and the result of molecular tests is given, “explains Macedo.

What are the advantages of this treatment? Dr. Macedo points out that with white therapies, compared to chemotherapy, people have a high percentage of response, being 60-80% with the former versus 20-30% of chemotherapies.

“There are faster responses too: in two weeks you start to see results, compared to chemotherapy, where they are seen in six weeks, in addition there are few adverse effects, there is brain protection against metastasis and therefore better survival” , indicated the doctor.

“Do not stay with the doubt. We are in a good time for oncology and patients should be empowered and ask all the doubts they have. There are already different ways of treating them, not just the traditional approach,” concluded the expert on these possible cancer treatments.

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