Study: COVID-19 may be the root cause of unknown hepatitis in children worldwide

There have been hundreds of recent outbreaks of acute hepatitis of unknown origin in children around the world. New research shows that COVID-19 (coronavirus disease 2019) may be the root cause.

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Study: COVID-19 may be the root cause of unknown hepatitis in children worldwide (Getty)

On the 14th, MedRxiv, a preprint platform for American medical journals, published a study report that had not been peer-reviewed, saying that children suffering from COVID-19 may significantly increase the risk of abnormal liver function. But most children with acute hepatitis were not previously reported to be infected with the new coronavirus, but instead were infected with adenovirus type 41, which does not attack the liver.

In a separate study published in the journal The Lancet Gastroenterology & Hepatology, the researchers noted that because these children are too young to be vaccinated, they may be vulnerable to COVID-19 infection. Symptomatic or asymptomatic and undetected.

If so, the researchers reasoned, the novel coronavirus in these children’s gastrointestinal tracts may have overreacted the immune system to adenovirus type 41, a flood of inflamed proteins that eventually lead to liver damage.

“We recommend testing the stool of children with acute hepatitis for the presence of 2019-nCoV, and looking for other signals that trigger liver damage, as the SARS-CoV-2 spike protein is a ‘superantigen’ that makes The immune system is overly sensitive.”

(Editor-in-Chief: Zhuang Yanyu)

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