The Rise of Covid Strain BA.2.86: Immune Resistance, Transmission Efficiency, and Global Impact

2023-09-06 06:08:00

“Covid strain BA.2.86” has 2-3 times more immunity than XBB.1.5. Dr. Teera reveals resistance to all antibodies currently used in treatment. Indicates that the performance is still the same as the current outbreak of XBB.x.

Covid strain BA.2.86 is being watched a lot After the current epidemic has spread in many areas.

However, the area of ​​interest is the transmission efficiency.

Most recently, Assoc. Chulalongkorn University Has posted a message via Facebook “Thira Woratanarat (Papa Mee Keen)” with a message indicating Covid strain BA.2.86 that

Update Pirola (BA.2.86)

Dr. Teera said that from the GISAID database, there are currently 42 cases reported from all over the world, including the Americas, Europe, Asia and Africa, with the latest 6 cases from the UK waiting to be uploaded.

There are also reports found in community wastewater from many countries such as the United States, Switzerland. including Thailand

Recently, BA.2.86 has a child as BA.2.86.1 with 2 additional mutations reported in the state of Colorado, USA.

Performance of BA.2.86

So far, three lab studies have been conducted, from Peking University in China, the Karolinska Institute in Sweden, and the Barouch lab, a collaboration between Harvard and Columbia Universities, USA.

The result is consistent in the same direction.

BA.2.86 was 2-3 times more immune-resistant than XBB.1.5, which was less than expected. But it’s a clear explanation that even the XBB family, which has dominated the epidemic for a long time because it’s known to be more immune to the virus than any other strain that has ever infected BA.2.86, is also more dodgy. BA.2.86 is resistant to drugs. All antibodies currently available for treatment Due to the nature of the mutation, BA.2.86 appears to be less potent in infecting cells than XBB.1.5 and EG.5.x. virus strains that the mutation may increase the ability to dodge the terrain increased The results of antibody studies in people previously infected with the XBB substrain showed that the resulting antibodies may provide some protection against BA.2.86. resulting in further evaluation that A new generation of vaccines in America and Europe are about to be made available to the public. Produced from strain XBB.1.5, it is likely to be effective for some protection. Including helping to reduce severe illness and can die

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However, the above results are based on in vitro studies in the laboratory. but in real life There are various factors Many more contributed to the epidemic of BA.2.86.

It is undeniable that BA.2.86 has been reported recently, starting with Israel. And found spread around the world in a few weeks, despite the population in the world being infected a lot Including having received enough basic vaccination Including the XBB.x strain that dominates the global epidemic. That’s the proof that Pirola or BA.2.86 should have a strong enough performance. To make it possible to spread throughout the world like this

each infection Whether it’s first or repeated infection, it has been proven to cause the risk of illness, death, including Long COVID in the long run.

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