U.S. research: Vaccination can best reduce the risk of lung and blood clots-Instant News-Free Health Network

Medical staff at a Texas hospital comfort a Wuhan pneumonia patient on December 4, 2020. (AFP file photo)

[Compiled by Guan Shuping/Comprehensive Report]A large-scale study in the United States explores whether vaccination against Wuhan pneumonia (new coronavirus disease, COVID-19) can protect infected persons from long-term sequelae. The results show that vaccination can reduce the risk of infection. There is a risk of lung problems or blood clots, but less protection against other problems.

The Washington Post and CNBC website reported on the 25th that this is part of a series of studies conducted by the U.S. Department of Veterans Affairs based on “breakthrough infections” in patients with pneumonia. According to the national medical records of 33,940 vaccinated and more than 113,000 unvaccinated patients with pneumonia Not so clear.

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Overall, the risk of developing long-term sequelae was only reduced by 15% 6 months after the study subjects were diagnosed. However, vaccination was the most effective in preventing blood clots and long-term lung problems. Compared with unvaccinated people, the risks were reduced. 56% and 50%, but there was little difference with or without vaccination in terms of neurological problems, digestive symptoms, kidney or other risks.

The research report was published in the journal Nature Medicine on the 25th. The first author of the report is Ziyad Al, director of the research and development department at the VA Saint Louis Health Care System in Missouri. -Aly) said, “This result is disappointing.” The research team had hoped to see that vaccination could provide more protection, especially now that the vaccine is the only line of defense, but research shows that the vaccine is in preventing the long-term sequelae of Wuhan pneumonia, ” Provides little protection.”

The World Health Organization (WHO) defines “post-armored lung symptoms” as symptoms that persist for at least 2 months and are unexplained by other diagnoses. According to WHO, up to 20% of the 500 million people with pneumonia in the world are estimated to have medium and long-term effects.

The VA analysis, believed to be the largest peer-reviewed study of the long-term sequelae of Wuhan pneumonia based on medical records in the U.S. to date, involved subjects vaccinated with either Moderna or Pfizer-BNT (Pfizer-BioNTech). ) vaccine, or the single-dose Johnson & Johnson vaccine.

However, the study did not assess the impact of booster doses, and could not tell whether different strains of the virus altered the vaccine’s effectiveness in preventing long-term sequelae. The breakthrough infection occurred in these patients at a time when earlier strains such as Alpha and Delta were at the peak of infection in the United States, excluding the later Omicron strains.

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