What is the difference between sequential immunization and vaccine “mixing”?Chinese disease control experts answer questions – China Daily

China News Service, Beijing, February 26 (Zhang Yilin) ​​At present, my country has launched the sequential immunization of the new crown vaccine, and many people still have some doubts: Is vaccination of the new crown inactivated vaccine from two manufacturers a sequential booster immunization? Is there any difference between sequential immunization and vaccine “mixing”?

The Joint Prevention and Control Mechanism of the State Council held a press conference on the 26th. The responsible comrades of the Ministry of Education, the Ministry of Transport, the relevant departments and bureaus of the National Health Commission and experts from the Chinese Center for Disease Control and Prevention attended to introduce the situation of epidemic prevention and control and vaccination.

On the 26th, the Joint Prevention and Control Mechanism of the State Council held a press conference to introduce the situation of epidemic prevention and control and vaccination.Photo by Zhang Yilin

15 provinces report new local confirmed cases in the past week

Mi Feng, a spokesman for the National Health Commission, said that in the past week, 15 provinces have reported new local confirmed cases. It is necessary to respond quickly, seize the key “window period” in the early stage of the treatment of clustered epidemics, and resolutely and decisively take various prevention and control measures to achieve “social zero” as soon as possible; pay close attention to the implementation of prevention and control measures for key groups, key places, and key links , and effectively minimize the risk of the spread of the epidemic.

The epidemic in Wuhan has spread to many places in Hohhot, and it is still at a high plateau

Wu Liangyou, deputy director of the National Health Commission’s Bureau of Disease Control and Prevention, introduced that recently, the domestic epidemic has been characterized by multiple, widespread and frequent occurrences, and the superimposed prevalence of Delta and Omicron variants.

Recently, the newly infected people in Suzhou, Jiangsu Province are mainly from the controlled population. The epidemic situation is on a downward trend as a whole, and the risk of community transmission is gradually decreasing. The local area is continuing to strengthen the management of closed and controlled areas.

The number of cases in Huludao, Liaoning Province has increased recently. This continuous tailing situation requires vigilance against the rebound and further spread of the epidemic.

The infected people in Heihe, Heilongjiang and Honghe, Yunnan are concentrated in the local area, and there are different transmission chains. The source of infection is still under investigation, and the epidemic has the risk of spreading.

The new cases of the epidemic in Lincang, Yunnan have been concentrated in a local middle school. It is necessary to transfer and isolate all teachers and students as soon as possible, and speed up the nucleic acid screening in key areas to prevent the further spread of the epidemic in the campus and community.

Shenzhen, Guangdong has a wide range of epidemic sites, complicated transmission chains, and a high risk of community transmission and spillover. The newly infected people in Dongguan are mainly distributed in an industrial park. The population density in this area is relatively high, and relevant cities in Guangdong are strengthening risk personnel. Check and control, speed up the push of assisted investigation information, and prevent the further spread of the epidemic.

There is a risk of further spread of the epidemic in Chengdu, Sichuan and Fangchenggang, Guangxi. The local area is speeding up the investigation and control of risk personnel to prevent the spread of the epidemic.

The epidemic in Wuhan, Hubei has spread to Beijing, Shandong, Hebei, Shanghai and other provinces (cities), and all localities are stepping up efforts to track and control risk personnel, speed up the investigation of spillover personnel, and prevent the further spread of the epidemic.

The epidemic situation in Hohhot, Inner Mongolia is still at a high plateau, but the risk of community transmission has decreased.

Judging from my country’s epidemic prevention and control experience, the current prevention and control measures are effective in dealing with the Omicron variant. The key lies in implementing the “Four Early Principles” and consolidating the “Quartet Responsibilities”.

The epidemic in Hong Kong is in a period of rapid spread and accelerated rise

Central government fully supports Hong Kong’s epidemic prevention and control

Wu Liangyou said that the people of the whole country are very concerned about the epidemic in Hong Kong. Since the outbreak, the central government has fully supported the prevention and control of the epidemic in Hong Kong, and the construction of eight makeshift hospitals assisted by the mainland is in full swing.

The National Health Commission and the Hong Kong SAR government held a video conference with experts in the medical treatment of new coronary pneumonia, and conducted in-depth and detailed discussions on specific technical issues. Two batches of experts from the mainland’s anti-epidemic medical and epidemic prevention team have been arranged to arrive in Hong Kong, and have exchanged views with relevant departments of the SAR government and medical workers.

In addition, other COVID-19 prevention and control experts in the Mainland will conduct video-link exchanges with the Hong Kong aid expert group every day to offer advice on Hong Kong’s anti-epidemic work. At present, the epidemic in Hong Kong is in a period of rapid spread and accelerated rise. The central government will continue to fully support Hong Kong’s epidemic prevention and control, and mainland experts will continue to work closely with their Hong Kong counterparts to do a good job in anti-epidemic work.

What is the difference between sequential immunization and vaccine “mixing”?

At present, my country has launched the sequential immunization of the new crown vaccine, and there are still some doubts from the public. Wang Huaqing, chief expert of the immunization program of the Chinese Center for Disease Control and Prevention, introduced at the meeting that sequential immunization is a vaccine using different technical routes. A vaccination strategy adopted to further reduce the risk of serious adverse reactions.

Wang Huaqing said that “mixed fighting” may be a concept proposed by the public or ordinary people. Professionally speaking, it is actually a vaccine with the same technical route, but the manufacturer is different. This time, the inactivated vaccine is used by one manufacturer, the second and third times. Fighting another manufacturer is actually all inactivated vaccines, all of which are the same technical route, not sequential immunization.

Is a sequential procedure required for booster immunizations that have already been vaccinated?

Wang Huaqing said that the booster immunization has been completed before the start of sequential immunization, that is, the group that has completed the booster immunization with the vaccine of the same technical route. According to the current regulations, there is no need for subsequent immunization.

In short, the current sequential immunization is based on inactivated vaccine immunization. If two doses of inactivated vaccine are given in the early stage, and the third dose of inactivated vaccine is given at an interval of more than 6 months according to the regulations, in this case, the same technical route is used for reinforcement, and subsequent immunization does not need to be used for reinforcement.

At this stage, for people aged 18 and above, if he has received two doses of inactivated vaccine, and the second dose is more than 6 months old, in this case, vaccines with different technical routes can be selected for sequential immunization, or the same vaccine can be selected. The inactivated vaccine of the technical route is used for booster immunization.

How can schools in medium and high risk areas do a good job in epidemic prevention and control?

At present, there are sporadic cases in many places in my country. How should schools in medium and high risk areas do a good job in epidemic prevention and control? Liu Peijun, deputy director and first-level inspector of the Department of Sports, Health and Arts of the Ministry of Education, said that when returning to school, the flow of teachers and students across provinces has increased, and the risk of campus epidemics cannot be ignored. The overall technical plan for prevention and control clarifies five specific requirements for schools in medium and high-risk areas to do a good job in epidemic prevention and control: primary and secondary schools, one province, one policy; college return arrangements, one school, one case; teacher and student health monitoring, one person for one file ; On-campus and off-campus protection should be strengthened together; online and offline teaching should be arranged as one.

Achieving the established goal of not spreading the epidemic due to the Spring Festival

The 40-day Spring Festival travel has ended. How are transportation services and epidemic prevention and control? Zhou Min, deputy director of the Emergency Response Office of the Ministry of Transport, said that the 2022 Spring Festival travel has ended, and relevant departments in various regions adhere to the principle of “preventing imports from outside and preventing rebound from inside”, refine and implement the requirements for epidemic prevention and control, and strengthen entry, waiting, and boarding. Efforts have been made to prevent and control the epidemic in all aspects of transportation, and strictly implement measures such as disinfection and ventilation, temperature measurement and code scanning, and control of passenger occupancy rate. (over)

[Editor in charge: Xu Dan]

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