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Why do geneticists advise to avoid inbreeding?

by archyde
Childwhile other diseases occur if one of the parents is a carrier of the gene, which may threaten the child’s infection with this disease.

Dr. Ikram Fateen, Professor of Biochemical Genetics, and former Vice President of the National Research Center in Egypt, confirms that we always advise against consanguineous marriage, because the majority of diseases Genetics result from recessive traits, which makes the proportion of genetic diseases increase with consanguineous marriage.

Ikram explains to Sky News Arabia that during the discovery of diseases in the Diagnostic Center for Genetic Diseases at the National Research Center, we found that between 88 to 90 percent of the diseases we diagnosed were mainly caused by inbreeding, adding that it causes many genetic diseases, especially That the analyzes carried out by the next to marriage Relatives do not include all diseases, and cover only 20 percent of these diseases.

Inbreeding is related to diseases

She added that: "Consanguineous marriage is responsible for many diseases such as disease "Gaucher" and sick "Metachromatic Leoko Destrophe"There are many diseases that we diagnose daily at the National Research Center, due to consanguineous marriage, and most of these diseases are among children, and some symptoms appear at an older age, which may be when a person reaches the age of 18 or 20 years, and some appear at the age of 30 years, but Most appear in childhood".

A professor of genetics at the National Research Center indicated that consanguineous marriage in some cases is related to deformities of children, and diseases that mostly lead to mental disabilities, physical disabilities, and multiple problems and may lead to premature death.

She also pointed out that consanguineous marriage sometimes causes the emergence of genetic diseases linked to organic and amino acids, which may exceed the limit, causing diseases, the most famous of which is phenylalanine disease (PKU), a genetic disease that causes intellectual disability, and if it is not discovered in the first week of birth so that the child is fed With special types of milk, the child is exposed to mental disability, and this disease is the main reason that prompted us to conduct a genetic survey for newborns, because diagnosing the disease during the first week and adhering to the special milk makes us able to treat the child’s condition, so that it grows normally, while every week the treatment is delayed. IQ coefficient of the sick child.

Symptoms that may indicate the presence of genetic diseases

The genetics professor advised the need to follow up the symptoms that appear on children well, pointing out that: "Attention should be paid to certain symptoms that may be related to genetic diseases, such as an enlarged liver or spleen, delayed speech and hearing, nervous spasms, or bone or joint problems, all of which are signs of genetic diseases that may cause multiple problems.".

The necessity of avoiding marriage with relatives up to the third degree

Dr. Ikram continued: "I always ask not to marry cousins, or cousins, or cousins, or cousins, and the matter is no different here between the relatives of the father or the mother, as I prefer to stay away from marriage with relatives of the second degree as well as the third".

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Genetic diseases are those that occur due to a defect in the genetic material of the individual, and they differ in their transmission to the fetus, there are some diseases that require both parents to be carriers of the gene for the disease to be transmitted to the fetus. Childwhile other diseases occur if one of the parents is a carrier of the gene, which may threaten the child’s infection with this disease.

Dr. Ikram Fateen, Professor of Biochemical Genetics, and former Vice President of the National Research Center in Egypt, confirms that we always advise against consanguineous marriage, because the majority of diseases Genetics result from recessive traits, which makes the proportion of genetic diseases increase with consanguineous marriage.

Ikram explains to Sky News Arabia that during the discovery of diseases in the Diagnostic Center for Genetic Diseases at the National Research Center, we found that between 88 to 90 percent of the diseases we diagnosed were mainly caused by inbreeding, adding that it causes many genetic diseases, especially That the analyzes carried out by the next to marriage Relatives do not include all diseases, and cover only 20 percent of these diseases.

Inbreeding is related to diseases

She added, “Inbreeding is responsible for many diseases, such as Gaucher disease, Metachromatic Leuko dystrophy disease, and others. At an older age, it may be when a person reaches the age of 18 or 20 years, and some appear at the age of 30 years, but the majority appear in childhood.”

A professor of genetics at the National Research Center indicated that consanguineous marriage in some cases is related to deformities of children, and diseases that mostly lead to mental disabilities, physical disabilities, and multiple problems and may lead to premature death.

She also pointed out that consanguineous marriage sometimes causes the emergence of genetic diseases linked to organic and amino acids, which may exceed the limit, causing diseases, the most famous of which is phenylalanine disease (PKU), a genetic disease that causes intellectual disability, and if it is not discovered in the first week of birth so that the child is fed With special types of milk, the child is exposed to mental disability, and this disease is the main reason that prompted us to conduct a genetic survey for newborns, because diagnosing the disease during the first week and adhering to the special milk makes us able to treat the child’s condition, so that it grows normally, while every week the treatment is delayed. IQ coefficient of the sick child.

Symptoms that may indicate the presence of genetic diseases

A professor of genetics advised the need to follow up the symptoms that appear on children well, pointing out that: “It is necessary to pay attention to certain symptoms that may be related to genetic diseases, such as an enlarged liver, or spleen, or delayed speech and hearing, or nervous convulsions, and problems of bones, or joints, These are all signs of genetic diseases that may cause multiple problems.”

The necessity of avoiding marriage with relatives up to the third degree

Dr. Ikram continued: “I always ask not to marry cousins, or cousins, or cousins, or cousins, and the matter is no different here between the relatives of the father or the mother, and I also prefer to stay away from marrying second- and third-degree relatives.”

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