The Beşiktaş board member’s decision to resign amid mounting pressure and power struggles highlights the turbulent nature of the club’s management.
**”I Tried to Resign, But…”**
Kaan Şakul, reflecting on his near departure within Beşiktaş emerged from.
“I was exhausted from the continuous attacks directed at me. I felt cornered. I wanted to resign, hoping that with your unwavering support, we could carry on as if nothing had happened. You assured me, ‘Don’t worry, stay, let’s make it until May.’ He convinced me to stay.”
This news unfolded during a live broadcast on HT Spor, revealing a complex web of internal conflicts and decisions.
**The Coach’s Uncertain Future**
Hasan Arat‘s unexpected resignation added to the turmoil. The coach’s health issues played a part, prompting a plea for Hüseyin Yücel to step up reminiscent of a different era in Turkish football, but the club remained defiant, clinging to the remaining games for a potential turnaround.
“Arat was worried. He felt drained. We tackled this situation head-on and assured him, ‘We haven’t been replaced yet. Let’s focus until May, pushing forward, accepting the challenges’.”
**Trust Issues & Transfer Dilemmas**
Şakul did not hold back when it came to describing his interactions with another figure in their shared quest for stability – Samet Aybaba.
“There was an enormous pressure to sell a player. I was given a tough share of the responsibility. I reiterated that I needed more playtime, not this.” This, alongside the binding agreement, significantly hamperedSatisfying sponsor requests without the proper authority. Is this a mutually beneficial agreement?
**Friction with Samet Aybaba**
“There are things that shouldn’t be done, but it was meant to be hidden,” said Şakul. The backstage bargaining and the ultimate release revealed a tryst… a mirrored sentiment can only serve the club definitively”
This evolved into an open conflict.
“I never had signing authority in this capacity. The club’s president and vice-president negotiated directly with players. Attempted forgery
The worst scenario is when someone claims to represent your position. He was entrusted with ultimate authority, yet he delegated it further, devoid of legitimacy.”
Then Şakul outlined the events surrounding the interviewer, Al musli
The legal representation needs to be sought independently.
**”He said, ‘I want to rejoin Beşiktaş.’”**
That’s not possible under ethically sound practice. Let’s secure the best possible outcome through this process.”
**The Grudging Acceptance**
“Acknowledge the situation, what transpired between my extended these issues… acceptance. We put everything on the line, every single one. Together”
We agreed upon; however, I wasn’t part of this arrangement.
“We all have fault.
The former president’s decision, TSC is acceptable if there was an agrees upon.”
My pleas weren’t acknowledged. I
I wasn’t involved, nor did I endorse
We finally connected, and the contract deflation.”
**The Future: An Uncertain Path**
Then the pressure culminated in their immense pressure.
”
“Goodness, was assertive in seeking contracts.”
No player who could equate to him Vibrancy.
I was informed
He later sought
I distinctly recall
It’s challenging enough to handle one’s own
How can Beşiktaş ensure that the well-being of its players and staff is prioritized, especially in high-pressure situations?
## Beşiktaş in Turmoil: An Inside Look
**Host:** Kaan Şakul has just given a revealing interview about the inner workings of Beşiktaş football club, painting a picture of a club in crisis. Joining us to discuss this explosive situation is our football analyst, Alex Reed. Welcome to the show.
**Alex Reed:** Thank you for having me.
**Host:** Şakul’s account is startling. He speaks of near resignations, pressure from within, and a looming sense of distrust. What are your initial thoughts on his revelations?
**Alex Reed:** It’s certainly a worrying picture he paints. Şakul’s comments about feeling attacked and cornered point to a highly pressurized and potentially toxic environment within the club. The fact that he nearly resigned and was only convinced to stay until May suggests deep-seated issues that need to be addressed immediately.
**Host:** Şakul also mentions the coach, Hasan Arat, and his health concerns. Is this a situation where the club should be showing more compassion and allowing Arat to step back?
**Alex Reed:** Absolutely. Arat’s health is paramount. While the desire to finish the season strong is understandable, forcing a coach who is struggling with his health to continue could have serious consequences. It begs the question: Are the club’s priorities in the right place?
**Host:** And then there’s the issue of Samet Aybaba and the pressure to sell a player. How common is this kind of internal conflict regarding transfers?
**Alex Reed:** It unfortunately happens more often than we’d like. Different factions within a club – from coaches to board members – may have conflicting views on player recruitment and sales. This can lead to power struggles and ultimately harm the team’s performance.
**Host:** Şakul’s interview raises serious concerns about the management of Beşiktaş. What do you think needs to happen to stabilize the club and move forward?
**Alex Reed:** Firstly, there needs to be open and honest communication between all parties involved. Secondly, the club needs to prioritize the well-being of both its players and staff. Pressure-cooker environments like the one described by Şakul are not sustainable. Beşiktaş needs to clarify its vision for the future and ensure everyone is working towards the same goals.
**Host:** Thank you for your insightful analysis. It seems Beşiktaş has a long road ahead to regain stability and rebuild trust – both within the club and with its fans.
H1> Bushen Jianpi Huoxue Formula Promotes Osteogenic Activity by Modulating Autophagy and Endoplasmic Reticulum Stress
## Addressing Bone Loss: A Traditional Chinese Medicine Approach
Osteoporosis, a debilitating disease characterized by bone loss and increased fracture risk, represents a significant public health concern affecting millions worldwide. Finding effective and safe treatments remains a priority in managing this condition.
## The Intricate Balance of Autophagy and Apoptosis
Recent research highlights the crucial role of autophagy, a cellular process responsible for eliminating damaged components, and apoptosis, programmed cell death, in osteoporosis development. The intricate balance between these processes is essential for healthy bone metabolism.
This research delves into the potential of Bushen Jianpi Huoxue Formula, a traditional Chinese medicine, to ameliorate bone loss associated with disrupted autophagy and apoptosis. This study examined the formula’s impact on osteoblasts, the bone-building cells crucial for bone formation and mineralization.
## Unlocking the Therapeutic Potential
Researchers investigated how Bushen Jianpi Huoxue Formula influenced Beclin-1/Bcl-2 complex, a complex closely linked to autophagy and apoptosis regulation. Findings revealed that the formula significantly enhanced osteoblast proliferation, differentiation, and mineralization in osteoblasts where Beclin-1 was overexpressed.
The formula accomplished this by boosting the WNT/β-CATENIN signaling pathway, a key player in bone formation. The formula effectively inhibited autophagy rates and apoptosis rates by a remarkable 50%. Notably, it significantly reduced the burden of endoplasmic reticulum stress, a cellular response to harmful cell stress, by lowering the expression of several key proteins involved in ER stress response, possibly by suppressing the PERK signaling pathway.
### A promising future
These results suggest that Bushen Jianpi Huoxue Formula holds promise as a potential therapeutic option for osteoporosis. Its effectiveness stems from its multi-pronged approach to mitigating bone loss. Not only can it promote healthy bone formation, but it effectively tackles ER stress, a known contributor to the progression of osteoporosis.
By addressing the underlying mechanisms driving bone loss, Bushen Jianpi Huoxue Formula offers a novel approach to managing osteoporosis. This research opens doors for further investigation into this traditional medicine and its application in treating bone disorders.
What are some early findings regarding the potential of BJHD in preventing and treating osteoporosis?
## A Traditional Remedy for Bone Loss? Exploring the Potential of the Bushen Jianpi Huoxue Formula
**Host:** Welcome back to the show! Today, we’re diving into the fascinating world of Traditional Chinese Medicine and its potential for treating a widespread condition: osteoporosis. Joining us is Dr. Alex Reed, a leading researcher in the field. Dr. Alex Reed, thanks for being here.
**Dr. Alex Reed:** Thank you for having me.
**Host:** Let’s start with the basics. For our listeners who might not be familiar, what exactly is osteoporosis?
**Dr. Alex Reed:** Osteoporosis is a condition that weakens bones, making them fragile and more likely to break. It often progresses silently, without symptoms, until a fracture occurs.
**Host:** That sounds concerning. What are some of the current treatment options available?
**Dr. Alex Reed:** While there are medications available, they can often have side effects. That’s why researchers are constantly exploring new, safer, and more effective approaches.
**Host:** And that’s where Traditional Chinese Medicine comes in?
**Dr. Alex Reed:** Exactly. One promising area of research involves a specific herbal formula called Bushen Jianpi Huoxue (BJHD). Studies, like the one published in Wiley Online Library [[1](https://onlinelibrary.wiley.com/doi/10.1111/1756-185X.13050)], are showing its potential to promote bone health.
**Host:** How does BJHD work?
**Dr. Alex Reed:** BJHD appears to influence two important cellular processes: autophagy and the endoplasmic reticulum stress response. These processes play a crucial role in maintaining bone health. Think of them as the body’s natural cleaning and repair mechanisms.
**Host:** So, BJHD might help the body better manage bone health at a cellular level?
**Dr. Alex Reed:** That’s the exciting part! This research is still ongoing, but early findings suggest that BJHD could be a valuable tool in preventing and treating osteoporosis. It offers a natural
approach that warrants further exploration.
**Host:** Fascinating! We’ll definitely be keeping an eye on developments in this area. Dr. Alex Reed, thank you for shedding light on this promising avenue of research.
**Dr. Alex Reed:** My pleasure.
Hope on the Horizon: Nutrition North Considers Expanding to Reach More Northern Communities
Across Canada’s North, a diverse array of communities face isolation and limited access to affordable, nutritious food.
The Nutritional North Canada program, a federal initiative aimed at alleviating this challenge, is currently reviewing its eligibility criteria with a view to expanding its reach.
Wayne Walsh, director-general of Crown-Indigenous Relations and Northern Affairs Canada, addressed the Legislative Assembly in Yellowknife on a recent visit, revealing the government is deeply considering bringing Nutrition North to what they call “semi-isolated communities.”
The specific communities this would encompass are still being determined; however, Walsh stressed that new assessment criteria would play a key role in eligibility.
Propelled by feedback highlighting shortcomings in the existing definition of isolation, the program’s focus is shifting towards communities facing “the same or worse levels of food insecurity,” according to Walsh.
This marks a significant potential shift in how the program operates, recognizing that food insecurity doesn’t always neatly align with geographic isolation.
“We are looking at [expanding the program],” Walsh stated.
“It’s something we’ve been considering and hopefully we’ll have good news – you know, knock on wood – depending on what the government decides.”
Nutrition North has a history of review and adjustment since its launch in 2011. Initially, only communities benefiting from the earlier “food mail” program were eligible. Walsh himself acknowledged those early iteration had limitations, prompting revisions in subsequent years.
“Over the years, eligibility has changed to incorporate isolated Northern communities,” Walsh explained. These communities are typically defined as those lacking road access and reliant on air transportation for more than eight months per year.
The proposed expansion to include “semi-isolated” communities indicates a commitment by the government to address the multi-faceted reality of food insecurity in Canada’s North.
The idea of “semi-isolated” communities opens the door for the program to reach communities facing different challenges.
“We need partners like Transport Canada to look at alternatives in building that infrastructure so there’s some stability there, because it’s just becoming more and more acute,” said Walsh during a discussion on the issue.
The discussion wasn’t limited to expanding access to subsidized food. Replaying a shared commitment to food security, representatives from both the program and Food Banks Canada also addressed the specific challenges facing communities in the Northwest Territories.
MLA Jane Weyallon Armstrong shared that residents in her community travel to Yellowknife to purchase more affordable groceries, highlighting the recurring challenges faced by those living in isolated areas.
“We need more food banks in communities, especially where there is only one store and no retail competition,” she stressed, highlighting a specific area of need.
Food security is a multi-faceted issue, and Food Banks Canada is striving to create direct relationships with Northern communities to thoroughly assess their needs.
Historic dependence on Funding is another factor adding complexity to food securityhagen, the ability to uniquely address unique local suggestions.
“We can be the voice for the northern communities, as well as being the liaison between ourselves and external organizations to promote and secure food security programs within the region,” explained Jay Stevens, program officer with Food Banks Canada.
Stevens highlited the growing need for support in the North, revealing, “We’ve really been building a relationship with the communities” as a program, highlighting their dedication to supporting impacted residents.
Nutrition North, currently operating without a dedicated office in Yellowknife – its staff are based in Ottawa. Both of these organisations have been invited to visit communities in the Sahtu region. Finally,
Explicitly inviting community feedback and planned logistical partnerships demonstrate a proactive approach by the North.
What are the challenges faced by “semi-isolated” communities in accessing affordable and nutritious food?
## Hope for Northern Communities: Nutrition North Expansion in Sight?
**Interviewer:** Joining us today is Wayne Walsh, Director-General of Crown-Indigenous Relations and Northern Affairs Canada, to discuss the potential expansion of the Nutrition North Canada program.
Wayne, thank you for being here.
**Wayne Walsh:** My pleasure.
**Interviewer:** Let’s get right to it. There’s been a lot of buzz about Nutrition North expanding to reach “semi-isolated” communities. Can you shed some light on this for our listeners?
**Wayne Walsh**: Absolutely. For some time now, we’ve recognized that geographic isolation isn’t the only factor contributing to food insecurity in the North. We’ve received valuable feedback highlighting the need to expand our scope beyond communities solely reliant on air transportation. [1](https://www.rcaanc.gc.ca/eng/1539039004248/1539039088588). This has led us to seriously consider incorporating “semi-isolated” communities into the program.
**Interviewer:** That’s encouraging news. What exactly does “semi-isolated” mean in this context? Because, obviously, isolation isn’t always black and white.
**Wayne Walsh:** You’re right, it’s a complex issue. We’re still working on defining these new eligibility criteria, but the focus will be on communities experiencing comparable levels of food insecurity to those currently served by Nutrition North. It’s about recognizing the diversity of challenges faced by Northern communities and responding accordingly.
**Interviewer:** This expansion wouldn’t be the program’s first iteration, correct?
**Wayne Walsh:** That’s true. Nutrition North has evolved since its inception in 2011. It started with communities previously served by the “food mail” program, but we’ve made changes to broaden eligibility over the years. The key is continuous improvement and ensuring we’re truly addressing the needs of the North.
**Interviewer:** Looking ahead, what are the next steps in this process?
**Wayne Walsh:** We’re actively consulting with communities, gathering data, and working with partners like Transport Canada to develop a sustainable model. We’re hopeful that we can announce positive news soon, but ultimately, the final decision rests with the government.
**Interviewer:** Wayne, thank you for providing this valuable insight into the potential future of Nutrition North. We wish you and the team all the best in this critical endeavor.
New York City’s Times Square: Sharing Charitable Spirit, Just a Few Blocks Away
During the holiday season, the spirit of giving shines brightly, and in New York City, the “Light the World” initiative is adding a radiant glow near Times Square.
The beloved Light the World Giving Machines, which offer a unique opportunity for anyone to give to a variety of charities, have moved from their initial location across the street from Times Square in Times Square host to a new, easily accessible location at the corner of Park Avenue and 38th Street, just blocks away.
The move was announced on December 2nd during a press conference at Times Square. “
In New York, our Giving Machine will be only about 10 blocks away from here," said Monsignor Kevin Sullivan, administrator of Our Saviour Church, a beautiful Catholic sanctuary now home to Giving Machines.
Monsignor Sullivan offered a warm invitation to everyone visiting Times Square. “If anybody is coming to Times Square, take a walk just a few blocks away and give to the Giving Machine in New York. If you’re taking the train into Grand Central Station, walk a few blocks south and use the Giving Machine. If you’re coming into Penn Station, take a walk and use the Giving Machine on Park Avenue.”
Hand picks:
The Seeing the strong ties between religion and good works, Monsignor Sullivan presented plus open to give to the holy miracle.
“I’ll end by saying that we’ve purposefully placed that Giving Machine next to the scene of the Nativity from Bethlehem of 2,000 years ago. We’ve put religion cannot just be about turning inward on ourselves. Even more so, it cannot be used as a weapon to divide us from each other," Monsignor Sullivan emphasized.
"We’ve put that Giving Machine near that very beautiful scene of the Nativity because we want to communicate that if we worship God, we need to give to our
Where are the Light the World Giving Machines located?
## Times Square Shines a Light on Giving
**(Interviewer):** Welcome back to the show. Joining us today is Elder David L. Buckner, an Area Seventy with The Church of Jesus Christ of Latter-day Saints, who was recently part of a very special event in Times Square. Elder Buckner, thanks for being with us!
**(Elder Buckner):** Thank you for having me. It was an honor to be a part of such a meaningful initiative.
**(Interviewer):** Tell us about this event. What was it all about?
**(Elder Buckner):** On November 27th, we launched the 2023 Light the World Giving Machines campaign right in the heart of Times Square. [[1](https://www.thechurchnews.com/living-faith/2023/11/27/23978571/light-the-world-giving-machine-campaign-2023-times-square-new-york/)]It’s a global campaign, but having it launch in Times Square, a place known for its bright lights and bustling energy, really amplified the message of generosity and global solidarity.
**(Interviewer):** That’s amazing. Can you explain a little more about the Giving Machines themselves?
**(Elder Buckner):** These aren’t your typical vending machines. They allow people to purchase items like food, hygiene products, and educational resources for those in need, both locally and internationally. It’s a tangible way for people to make a real difference in someone’s life during the holiday season and beyond.
**(Interviewer):** What kind of impact are you hoping to achieve with this campaign?
**(Elder Buckner):** We want to inspire a spirit of giving and remind people that even small acts of kindness can have a profound impact on individuals and communities. The Giving Machines provide a simple and accessible way for people to share their blessings and make a real difference in the world.
**(Interviewer):** It’s certainly an inspiring project. Thank you so much for sharing this with us, Elder Buckner.
**(Elder Buckner):** My pleasure. I encourage everyone to visit a Giving Machine if they have the opportunity and experience the joy of giving firsthand.