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Press information | Health North Hesse

by James Carter Senior News Editor

Revolutionary Cancer Diagnosis Technology Arrives in Northern Hesse – Faster, More Precise Treatment on the Horizon

Kassel, Germany – A significant leap forward in the fight against cancer is unfolding in Northern Hesse, as the pathology department at MVZ Gesundheit Nordhessen at the Kassel Clinic unveils its new Next-Generation Sequencing (NGS) technology. This isn’t just an upgrade; it’s a turning point in how tumor diseases are diagnosed and treated, promising faster, more targeted therapies for patients in the region and beyond. This is a breaking news development with significant SEO implications for those seeking information on advanced cancer care.

Unlocking the Molecular Secrets of Cancer

For years, cancer treatment has been evolving towards personalization – tailoring therapies to the unique genetic makeup of each tumor. But achieving that level of precision requires increasingly sophisticated tools. The newly installed Genexus system from Thermo Fisher Scientific represents the latest advancement in NGS, allowing pathologists to analyze tumor DNA with unprecedented speed and accuracy. Prof. Dr. Irina Berger, head of the pathology department, explains, “With this fully automated system, we can make personalized treatment of tumor patients more efficient and targeted.”

The clinic has been utilizing NGS technology for over five years, but this new generation system dramatically enhances their capabilities. Dr. Salima Mrabet-Dahbi, head of the NGS laboratory, is particularly enthusiastic about the system’s speed and sensitivity. “My motivation is to be able to give all patients access to the best possible therapies. We must understand every sample we receive not just as a number, but also and above all as a personal fate that lies behind it,” she passionately states. The investment, totaling several hundred thousand euros, underscores the clinic’s commitment to cutting-edge cancer care.

BRCA Testing and Beyond: A Comprehensive Genetic Scan

While NGS has broad applications, certain tests are particularly crucial. BRCA testing, which identifies mutations in genes responsible for DNA repair, is a cornerstone of treatment planning for prostate, pancreatic, stomach, and gynecological cancers (breast and ovarian). Detecting these mutations is now a covered service by statutory health insurance for many patients, though eligibility varies based on tumor stage and type. But the new system doesn’t stop at BRCA. It allows for a comprehensive analysis of all genetic changes within cancer-inducing genes, and can even identify potential germline mutations – hinting at hereditary cancer risks within families. However, confirming a hereditary risk requires further genetic testing for the patient and potentially their relatives.

Speed and Efficiency: From Sample to Treatment Faster

The impact of this technology isn’t just about *what* can be tested, but *how quickly*. The Genexus system can analyze 16 to 32 patient samples in a single run, delivering results within a single working day. “Thanks to this new NGS technology, we can now inform colleagues in the clinics about the individual molecular tumor profile at an impressive speed, so that they can discuss their therapy options with patients much earlier,” explains Dr. Mrabet Dahbi. This accelerated turnaround time is critical, as it allows oncologists to initiate the most appropriate treatment plan sooner, potentially improving patient outcomes.

Opening Doors to Innovative Therapies and Early Detection

The increased sensitivity of the new system also means it can detect therapy-relevant mutations at very early stages of tumor development, potentially leading to earlier diagnoses and interventions. Furthermore, the technology expands access to both current and “off-label” therapies – treatments approved for other conditions but showing promise in specific cancer cases. A particularly exciting innovation coming in May is HRD diagnostics (homologous recombination deficiency), which analyzes a panel of 500 genes to assess a tumor’s ability to repair DNA damage. This will provide a deeper understanding of treatment responsiveness.

This investment by MVZ Gesundheit Nordhessen isn’t just a local story; it’s a testament to the ongoing revolution in cancer care. By embracing these advanced technologies, the clinic is empowering its physicians to deliver the most precise, effective, and compassionate treatment possible, offering renewed hope to patients facing a cancer diagnosis. For more information about the pathology department and its services, visit their website.

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