Astrazeneca vaccine: list of known side effects

Approved on February 15, 2021 by the WHO as part of the fight against Covid-19, the Astrazeneca vaccine very early on raised heated controversy. Between the severe influenza syndromes observed with its injection, and the risk of thrombosis, discover in this article, the full point of the known side effects of Astrazeneca.

Common and minor side effects of the Astrazeneca vaccine

If there is one vaccine that has undergone enough controversy around the world, it is Astrazeneca. Several times rejected, then rehabilitated, its arrival on the market had however aroused great enthusiasm around the world.

Indeed, its relatively low cost and its storage conditions represent its greatest assets. Unlike other vaccines, Astrazeneca can properly be stored in refrigerators available everywhere on the market. Unfortunately, a great controversy will be born around this vaccine.

The debates will largely revolve around some of his Side effects suspected of causing risk of blood clots. From this confusion, the categorizing these side effects to better locate populations.

Under the minor side effects that may be experienced following the injection of the Astrazeneca vaccine, we can cite among others:

  • The flu symptoms manifested by high fevers, headaches and even body aches;
  • Some cases of vomiting and diarrhea;
  • The fatigue, chills and nausea ;
  • Decrease in appetite, dizziness and drowsiness;
  • Lymphadenopathy, arthralgia and myalgia;
  • Rashes and erythema ;
  • Respiratory disorders and edemas;
  • Muscle pain and increased heart rate ;
  • Etc.

In short, more than 1000 cases of side effects have been collected and analyzed by specialists from the US drug agency.

These discoveries aroused everyone’s curiosity, and more particularly that of the ANSM (National Agency for the Safety of Medicines and Health Products). It now follows closely the news related to the Astrazeneca vaccine and its adverse effects. Weekly reports are also regularly produced for this purpose, to keep public opinion informed.

You will understand, the side effects of the Astrazeneca vaccine are combed through to allow people to be vaccinated in peace.

Rare side effects

As mentioned earlier, there has been a lot of talk about the rare side effects of the Astrazeneca vaccine. Apart from the cases of myocarditis and pericarditis observed in some patients, especially in Europe, we can note, among others:

The risks of thrombosis

In March 2021, France, like many other countries, was forced to suspend injections of the vaccine. Astrazeneca. Indeed, risk of thrombosis had been raised in people having received doses of this vaccine as part of the fight against the coronavirus.

Alerted, European Medicines Agency (EMA) has quickly carried out studies to review the risks associated with the injection of Astrazeneca. At the end of these, the reports filed confirm both the efficacy of the coronavirus vaccine, and the risk of thrombosis that may result from its injection.

However, the experts made it clear in their report that the occurrence of this complication can be relegated to the rank of rare side effects of the vaccine. This is explained in particular by its low frequency, the researchers having discovered only about ten cases out of several million people vaccinated in Europe.

Although based on scientific facts and some statistics, these statements have failed to dispel the concerns of the people. In the United Kingdom, for example, following the detection of around thirty cases of thrombosis and a few deaths, the country has opted to take appropriate measures. The use of the Astrazeneca vaccine has been banned outright on people under the age of 30.

With 30 cases of thrombosis recorded on May 7, France will opt for more drastic measures. The Astrazeneca vaccine will only be recommended for people over the age of 55. In addition, a minimum of 12 days should be observed between the injection of the first and the second dose of the vaccine.

It should also be noted that serious complications have been noted in a few people who have suffered from thrombotic syndrome. These include the forms:

  • Arterial venous thrombosis, which can be very serious;
  • Splanchnic venous thrombosis;
  • And thrombosis of the cerebral venous sinuses.

In short, after injection of the Astrazeneca vaccine, it is recommended consult a doctor quickly in case :

  • Convulsions ;
  • Shortness of breath;
  • Severe headache;
  • From abdominal pain ;
  • Loss of visual acuity;
  • Pain in the chest;
  • From swelling in the legs ;
  • Etc.

Haematological disorders

In the list of rare side effects of Astrazeneca vaccine, low risk of blood disorders were noted by Scottish researchers. This discovery comes from a study carried out on more than 5 million people who received a first dose of this vaccine.

The good news here is that researchers have shown that this pathology is benign and resolving. This means that it does not pose a great danger to people who have received doses of the Astrazeneca vaccine.

Public Health Scotland will also confirm the data revealed by Scottish doctors in the columns of the very famous scientific journal Nature Medicine.

Clearly, haematological disorders are also relegated to the rank of rare side effects because of their low degree of occurrence and nuisance. It is also said that the risks associated with contamination with the coronavirus are higher than those generated by these disorders.

In other words, the concerns raised by the potential risks of haematological disorders are certainly legitimate, but disproportionate.

Capillary leak syndromes

Rare cases of capillary leak syndromes were also noted following the injection of the Astrazeneca vaccine. It is indeed a rare sickness responsible for the plasma leak in the blood vessels. It manifests itself by:

  • Feelings of weakness;
  • A drop in blood pressure;
  • Rapid and unjustified weight gain;
  • Of rapid and incomprehensible swelling of the lower and upper limbs;
  • Etc.

As you may have guessed, the appearance of these symptoms following the injection of the Astrazeneca vaccine requires rapid and efficient management.

It is also recommended for vaccinated people to quickly seek medical attention in the event of these symptoms. This is why it is formally prohibited for people with medical history related to capillary leak syndrome to receive doses of this vaccine.

Guillain-Barré syndrome

The Guillain-Barré syndrome, this is the other side effect of the Astrazeneca vaccine found in people vaccinated in India as well as in England. A total of 7 cases have been reported in the city of Kochi, compared to 11 in a hospital in Nottingham. Even if France has still not identified a case on its territory, the WHO wished to alert the world to the risks of its occurrence.

From the reported cases, it emerges that the pathology usually manifests itself about ten days after the injection of the Astrazeneca vaccine. In actual fact, Guillain-Barré syndrome manifests itself as a immune system failure that damages part of the nervous system. The consequence is disastrous and can be manifested by:

  • Persistent muscle weakness;
  • And, a loss of sensation in the arms and hands.

Let us remember for all intents and purposes that up to this day, researchers are struggling to prove the link between this vaccine and Guillain-Barré syndrome. It has also been reported that most people who have suffered from these side effects were in fact prone to Guillain-Barré syndrome.

Still, this vaccine is prohibited for people with a medical history with this pathology to avoid possible risks of complications.

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