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Lack of exercise among adults and especially among adolescents is a global health problem, but when it comes to exercising, countless temptations arise that try to prevent it. But how does our brain decide whether to exercise or not?

An experiment with mice has revealed that the decision is mediated by a brain chemical called orexin and the neurons that produce it, a finding that if transferred to humans could help develop strategies to encourage physical activity in people.

The results of the experiment, conducted by researchers at ETH Zurich (Switzerland), are important because, according to the World Health Organization, 80% of adolescents and 27% of adults do not exercise enough, while obesity is growing at an alarming rate in the population.

“Despite these data, many people manage to resist the constant temptations and get enough exercise,” says Denis Burdakov, Professor of Neuroscience at ETH Zurich.

Orexin, a chemical messenger

Orexin is one of more than a hundred messenger substances active in the brain, like serotonin or dopamine, but it was discovered relatively late, about 25 years ago. Scientists are only now clarifying its functions.

Dopamine is a key substance for personal motivation. “Our brain releases dopamine both when we eat and when we exercise, but it doesn’t explain why we choose one over the other,” says Burdakov.

To find out, the team devised an experiment in which mice were given free choice between eight different options in ten-minute trials.

These included a wheel they could run on and a “smoothie bar” where they could enjoy a standard strawberry-flavored milkshake.

In the experiment, they used two groups of mice: one with normal mice and another in which the orexin system had been blocked.

Mice with an intact orexin system spent twice as much time on the running wheel and half as much time on the shake bar as mice whose orexin system had been blocked.

The behaviour of the two groups did not differ in experiments in which the scientists only offered the mice the running wheel or the shake. “This means that the main function of the orexin system is not to control how much the mice move or how much they eat,” says Burdakov.

“Rather, it appears to be critical to making the choice between the two when both options are available.” Without orexin, the decision was clearly in favor of the shake, and the mice forwent exercise in favor of eating, the study said.

The researchers at ETH Zurich hope to verify these results in humans, since the brain functions involved are practically the same in both species.

“By understanding how the brain arbitrates between food consumption and physical activity, we can develop more effective strategies to tackle the global obesity epidemic and related metabolic disorders,” says Daria Peleg-Raibstein, a researcher at ETH Zurich and co-author of the study.

INSIDE Indo, a music aggregator in Indonesia, announced the launch of the latest single from the band Lalahuta entitled Kamu Yang Sakit, a work by renowned songwriter Raguel Lewi.

Collaborating with Celebrities Radio Jakarta, the song was introduced to the public exclusively through a Hearing Session event held on Tuesday (6/8) at Wayang Bistro, Kota Kasablanka Mall, South Jakarta.

Not only did they listen to the song, the exclusive premiere of the Official Music Video for Kamu Yang Sakit during the event also received a good response from everyone present.

“We have been partnering with Lalahuta and El (Raguel Lewi) for a long time. We brought them together until finally this song (Kamu Yang Sakit) appeared. Both of them have extraordinary potential in the Indonesian music industry,” said Inside Indo Project Manager Kevin Daniel, Tuesday (6/8).

The Lalahuta Band consisting of Kevin Widaya (Vocalist), Boni Eko (Drummer), Allain Hizkia (Bass), and Beno Louloulia (Guitar) feels very proud to perform the single Kamu Yang Sakit. By still prioritizing the Pop Ballad music genre that is full of dynamics, this song is a new color for Lalahuta.

“There is no total change in the color of the music in this single. The sound remains the same. But the lyrics are awesome. Kevin (New Vocalist) is very appropriate to bring this song. And Kevin in Lalahuta is actually not a new person. He has long helped Lalahuta on several occasions,” said Boni, the drummer who is also the driving force of the Lalahuta band.

Also read: Collaborating with Ecko Show, Qahla Releases Single Sirkel Toxic

“Lalahuta is used to music lyrics about heartbreak, broken home, hurt and disappointment. So this song is very fitting for Kevin to sing. When Inside Indo and El offered this song, we immediately agreed,” Boni continued.

The creator of the song Kamu Yang Sakit, Raguel Lewi, said that when he received the offer to collaborate with Lalahuta, he immediately thought about creating appropriate song lyrics for the band that was formed in 2013.

“I immediately made this song with a fairly quick process. As soon as I was offered to collaborate with Lalahuta, I knew this was not just any band. That’s why the lyrics of Tuhan Baik, Kamu Yang Sakit immediately appeared and turned out to be quite a kick and they (Lalahuta) liked these lyrics. We worked on the music arrangement together,” said El.

Also read: Feath Collaborates with Nanda from MIKA on Single Asa

Before releasing the single Kamu Yang Sakit, Lalahuta had released hit songs such as their first debut entitled Tersenyum Kembali.

The success of this single was followed by their other hits, such as Wait What Again, Never Wrong, and Make What Try, which were produced by Laleilmanino.

From 2020 to 2023, Lalahuta released the singles Radar and 1 2 3, which were tributes to their musical roots and love letters to Urban Pop music.

In 2024, Lalahuta introduced Kevin Widaya as a new vocalist who has been active in the Indonesian music scene.

On August 8, 2024, Lalahuta is also ready to pamper the ears of her listeners by releasing her latest original single entitled Kamu Yang Sakit. (Z-1)

The Palestinian organization Hamas has announced on Tuesday that their political office The new head will be Yahya Sinwar۔

Previously in this position Ismail Haniya Fize, but he was accused of an alleged crime in Tehran last week He was killed in an Israeli attack.

61-year-old Yahya Sinwar is said to have died on October 7 agitation was one of the few planners of the attack on Israel.

Since then, Israel has made unsuccessful attempts to locate them during the Gaza offensive.

According to media reports, the Israeli army attacking Gaza is searching for Sinwar with the help of drones, sensitive spy equipment and human intelligence, but so far no trace of him has been found.

They are probably hiding somewhere in the underground tunnels of Gaza.

According to the Associated Press, the selection of Yahya Sinwar, who has worked for years to build up Hamas’s military power and is considered by Iran, is a clear indication that Hamas is ready to deal with the 10-month destruction of Israel’s war in Gaza and Sinwar’s actions. The leader is ready to continue fighting even after the assassination of Ismail Haniyeh.

It is also likely to infuriate Israel, which has put Sinwar at the top of its hit list since the October 7 attack.

The announcement of Sinwar’s nomination has come at a time when the situation in the region is volatile.

Iran has vowed revenge against Israel for Haniyeh’s killing, and Lebanon’s Hezbollah has threatened to retaliate after Israel killed one of its top commanders in an airstrike in Beirut last week.

Israel has vowed to ‘exterminate’ Sinwar, after Prime Minister Binyamin Netanyahu compared him to Hitler.

Israeli attacks on Gaza During the exchange of prisoners between Israel and Hamas, the name of Yahya Sinwar came to the fore and it was said that this exchange was possible because of him.

Although talks between Hamas and Israel have taken place in Egypt and Qatar, according to a New York Times report, Sinwar is believed to need the negotiators’ approval.

Salah al-Din al-Awadah, a member of Hamas and a political analyst, told the New York Times that no decision could be made without consulting Sinwar.

Al-Awawda became a friend of Sinwar during his imprisonment in Israel in the 1990s and 2000s.

He said that Sinwar is ‘not some kind of manager or director, he is a leader.’

Israel’s most wanted man

Rear Admiral Daniyal Haghari, spokesman for the Israeli Defense Force, said after the October 7 attack, ‘This attack was decided by Yahya Sinwar. Therefore he and his companions are dead’, meaning that Israel is determined to kill them.

Among Sinwar’s associates is Mohammad Zaif, the commander of the Izz al-Din al-Qassam Brigades, the military wing of Hamas.

Last week, Israel claimed that Mohammad Zaif was killed, but Hamas denied this.

Hugh Lovatt, a senior policy fellow at the European Council on Foreign Relations (ECFR), told the BBC that “although Zaif was behind the planning of the October 7 attack because it was a military operation, Sinwar was ‘probably part of the group that planned it.’

In December last year, he addressed a rally in Gaza and said that Hamas was preparing to launch a major attack on Israel.

He had said, ‘Inshallah we will rain on you in the form of a storm. We will rain endless rockets at you, we will come at you with an infinite flood of troops, we will come at you with millions of our people.’

Hatred of Sinwar in Israel has reached such an extent that Israeli singer Renata Bar performed in front of IDF soldiers, changing the lyrics of the Arabic song ‘Ya bint al-Sultan’ to say, ‘Ya Yahya Sinwar. , you die tomorrow.’

After the October 7 attacks, a statement by Sinwar came to light in which he warned, “The occupying leaders should know that October 7 was only a rehearsal.”

‘Hello, I’m Yahya Sunwar, you are safe here’

According to the Reuters news agency, an 85-year-old Israeli woman, who was imprisoned by Hamas on October 7 and released two weeks later, said on November 29 that she met Gaza leader Yahya Sinwar while in prison and told him. Asked why they attacked peace workers like me.

85-year-old Yoshiod Lifshitz was captured by Hamas militants from his village of Ner Oz in Israel on October 7 and imprisoned in Gaza.

He told the Israeli newspaper Davar that he encountered Sinwar when he met the hostages in an underground tunnel where Hamas was holding them hostage.

According to the Israeli newspaper Jerusalem Post, another female prisoner who was released said that Sinwar came to the tunnel where she and other prisoners were kept and asked them how they were doing, and told them in fluent Hebrew not to harm them. will

“One of the released Israeli POWs said that Yahya Sinwar entered and introduced himself in Hebrew, ‘Hello, I’m Yahya Sinwar and you are safe here,'” X user Haya wrote in a post. Nothing will happen to you.’

According to Israel’s Channel 12, the Israeli security agencies also confirmed this statement of the Israeli prisoner.

Hamas leader Yahya al-Sinwar speaks during a rally on April 14, 2023 (Mohammed Abid/File Photo AFP)

22 years in Israeli prisons

61-year-old Yahya Sinwar is also known as Abu Ibrahim. He has spent 22 years in Israeli prisons.

He was serving a life sentence in an Israeli prison until 2011, when he was released along with other Palestinian prisoners in exchange for Gilad Shalat, an Israeli soldier held captive by Hamas.

Gilad Shalat was captured by Hamas in a 2006 ambush inside the Gaza Strip in exchange for Israel’s release of 1,027 prisoners, including hundreds of Palestinians convicted of attacks against Israeli soldiers and civilians. had gone

Six years after his release, Sinwar was replaced by Ismail Haniyeh as the head of Hamas’s military wing in February 2017 after a secret election process. Haniyeh later became the head of Hamas.

‘Prisoner No. 1’

Yaron Blum, an official at Israel’s Shin Bet intelligence agency, said in an interview with Israel Radio after Yahya Sinwar’s election that Yahya was ‘prisoner number 1.’

Blum also said that ‘Sinwar has a charming personality and is not corrupt.’

He had said that Sinwar believed in action and any kind of reconciliation with them would be very difficult.

According to Ehud Yari of the Washington Institute for Near East Policy, Sinwar managed to establish himself as a leader in the prison and was instrumental in negotiating with prison officials and maintaining discipline among the inmates.

According to a report by the British newspaper Guardian, a former Israeli interrogator who interrogated Sinwar in prison said that during his imprisonment in prison, Sinwar refused to talk to any Israeli and he punished other prisoners himself. used to speak to the Israelites.’

“He is 1000 percent determined and 1000 percent violent,” the investigator said.

But at the same time, the Guardian wrote that Sinwar is “a shrewd political activist with a sharp mind.”

According to the Guardian, from the way in which Sinwar was released, he concluded from his experience that the only way to free Palestinians imprisoned in Israeli prisons is to be arrested by Israeli soldiers.

A journalist who met Sinwar at the time told the Guardian that ‘Sinwar was so focused that it seemed as if the rest of the world did not exist for him.’

Proficiency in Hebrew

Ehud Yari says that Sinwar used to read Hebrew newspapers and always spoke to them in Hebrew.

His proficiency in Hebrew was such that he gave an interview in Hebrew a few months before his release in 2011, suggesting that he had become a ‘moderate’ in the eyes of the Israeli authorities.

The Financial Times quoted an official who interrogated Sinwar by the Israeli intelligence agency Shin Bet as saying that in prison, Sinwar “used to read books about Israeli figures such as Vladmir Jabotinsky, Menachem Begin and Yitzhak Rabin.”

Fluent in Hebrew and spending a long time in Israeli prisons, Sinwar considers himself an expert on Israeli politics and culture.

Hamas leader Yahya Sinwar waves as he arrives at a rally to mark the 31st anniversary of the founding of Hamas in Gaza on December 16, 2018. (File photo AFP/Saeed Khatib)

Water drips from the roofs

Sinwar’s family hails from the Palestinian village of al-Majdal Ashqlan, from which Israel expelled Palestinians in 1948. Now this area is part of the Israeli city of Ashkelon.

Sanwar was born on October 7, 1962 in Khan Younis. He was just five years old when Israel captured this city.

He writes in his book ‘Thorns and Flowers’ (Al-Shouk wa Al-Qarnafal) that ‘the winter of 1967 was very heavy, the spring was not even called when it suddenly started raining and the houses of the refugee camp in Gaza City were flooded. I drowned. The flood water entered our house.’

He writes that at that time he was at home with his three elder brothers and one sister who got scared by the flood.

‘My father and mother picked us up in their arms before the floor was wet. My mother lifted the bed before the water entered the house. I was the youngest so I clung to my mother.

‘At night, my mother used to keep aluminum pots under the roof to catch the raindrops from the roof.

‘Whenever I tried to sleep, I would hear the tap of the water. When the pots were full, my mother used to empty them.’

As a teenager, Sinwar joined the Muslim Brotherhood movement in Gaza, which changed its name to the Hamas movement in late 1987.

Sinwar studied at the Islamic University of Gaza and earned a bachelor’s degree in Arabic.

During his studies at the university, he was also the head of the Muslim Brotherhood’s student wing ‘Islami Bloc’.

Sinwar was one of the founders of the Muslim Brotherhood’s security wing in 1985, known as Majid. Its main goal was to resist the Israeli occupation of the Gaza Strip.

Lessons learned from prison

Although Sinwar has stayed away from the media, he has also held press conferences with the international media on some important occasions.

In 2018, Daniel Eastern, the correspondent of the American organization NPR, participated in such a press conference.

According to him, Sinwar said that he formulates his strategy with the help of lessons learned in Israeli prisons. Sinwar said that ‘just as the prisoners in the prison go on hunger strike for their rights, the Palestinians are protesting against their jailers to improve the conditions in Gaza.’

Eastern says that the future of Hamas depends to a large extent on Sinwar, which is why Israel, which is determined to destroy Hamas, has put Sinwar on its hit list.

Israel’s failure to understand the beauty

Israel has nearly 40 years of experience in dealing with swindlers, but they did not understand swindlers and therefore fell into a false sense of complacency.

Before the October 7 attack, Israel viewed Sinwar as a ‘dangerous extremist’, however, according to a report in The Times of Israel, Israel did not consider him a real threat because it believed that Sinwar was focused on Gaza. It is focused on consolidating Hamas’s rule and securing economic concessions.

According to a Fox News report, Michael Milstein, head of the Palestinian Studies Forum at Tel Aviv University’s Dayan Center, said, “Sinwar represents the second generation of Hamas leaders and has the skills to lead not only Gaza but the movement as a whole.” is capable of.’