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The entertainment industry is mourning the loss of Eric Dane, the actor best known for his role as Dr. Mark Sloan on the long-running medical drama Grey’s Anatomy. Dane passed away on February 19, 2026, at the age of 53, following a battle with Amyotrophic Lateral Sclerosis (ALS), his representative confirmed to USA Today [1]. The outpouring of grief from his former colleagues highlights the impact he had both on and off screen.
Dane first appeared on Grey’s Anatomy as a guest star in Season 2, exactly 20 years before his death, earning the nickname “Dr. McSteamy” [1]. He became a series regular from Seasons 3 through 8, and made a guest appearance in 2021. His character’s departure in the Season 9 premiere left a void for many fans. The actor’s diagnosis of ALS was made public in April 2025 [4], and he subsequently became an advocate for awareness and research into the disease.
Kim Raver, who played Dr. Teddy Altman alongside Dane on Grey’s Anatomy, shared a heartfelt tribute on Instagram, accompanied by photos of the pair both on and off set. Raver wrote, “Eric was a light. You’d observe it effortlessly shine from him on the set of Grey’s as well as when he was with Rebecca [Gayheart] and the girls.” [1] and [4]. She recalled his comedic timing and the joy he brought to the filming process, noting how he could deliver a line with “perfect comedic timing” that would “floor you.”
Patrick Dempsey, who portrayed Dr. Derek Shepherd and shared many scenes with Dane, expressed his sadness upon hearing the news. Speaking on the U.K.’s Virgin Radio, Dempsey said he had been texting with Dane and spoke to him about a week before his death, noting that Dane was “really starting to lose his ability to speak” [1]. He remembered Dane as “the funniest man” and someone who brought “so much fun” to the set, praising his sense of humor and easygoing nature. Dempsey likewise highlighted the “wonderful mutual respect” they shared.
Kevin McKidd, known for his role as Dr. Owen Hunt on Grey’s Anatomy, also shared his grief, calling Dane a “light” and a “buddy” who brought a special energy to the set [2]. James Pickens Jr. Also posted a tribute on social media, joining the chorus of colleagues remembering Dane fondly [4].
Dane’s representative stated that he spent his final days surrounded by his wife, Rebecca Gayheart, and their two daughters, Billie and Georgia, who were “the center of his world” [1]. His commitment to raising awareness for ALS research during his illness underscores his lasting legacy beyond his acting career.
As the Grey’s Anatomy family and fans continue to mourn, the focus will likely shift towards supporting ALS research and advocacy efforts, carrying forward the passion Dane championed during his final months. The impact of his work and the warmth of his personality will undoubtedly be remembered by those who knew him and those who enjoyed his performances.
Share your favorite memories of Eric Dane and his work in the comments below.