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Depression: the secret of ketamine finally unlocked?

Posted Oct 7, 2022, 2:00 PMUpdated on Oct 7, 2022 at 2:07 PM

At the heart of depression are the negative beliefs that depressed people develop regarding themselves, the world, and the future. Dangerous, because they pave the way for suicidal thoughts, these negative beliefs are also tenacious: they remain intact even following the patient has received positive information which would normally tend, in a healthy subject, to counterbalance them.

Unfortunately, conventional antidepressants leave on the sidelines no less than a third of depressives, known as “resistant”. It is for these left behind that hundreds of clinical trials have been devoted, since the beginning of the 2000s, to ketamine, an anesthetic commonly used since the 1960s and which was discovered by chance, there has a twenties positive effects on mood.

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