2023-06-19 08:38:29
38.4 million people were living with HIV in 2021 worldwide. For several years, the virus is present in certain white blood cells of the lymph nodes and multiplies. However, this is a so-called latency phase during which the immune system is still functional. ” HIV is very intelligent. Over time, it evolved to have epigenetic control of its expression, remaining silent to hide in the brain from immune clearance. We are beginning to unravel the unique mechanism that enables HIV latency in brain microglia,” reports lead author Guochun Jiang, an assistant professor in UNC’s Department of Biochemistry and Biophysics and a member of the UNC’s HIV Treatment Center. ‘A C.
“Although current therapies, such as current antiretroviral therapy, can successfully block virus replication, they cannot eradicate latent HIV. If treatment is interrupted, the virus can rebound following latency and restart the progression of HIV infection to AIDS,” details the latest study by American scientists from the HIV Cure Center at UNC School of Medicine, from the University of California at San Diego, Emory University and the University of Pennsylvania. These researchers wanted to determine where the latent cells were hiding in the body. Their findings were published in the Journal of Clinical Investigations.
These confirm that the immune cells that…
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