Home » News » If the pain does not improve even after changing the medication… The key to treatment is ‘normalization of brain circuits’[이진형의 뇌, 우리 속의 우주]

If the pain does not improve even after changing the medication… The key to treatment is ‘normalization of brain circuits’[이진형의 뇌, 우리 속의 우주]

‘Brain Beats Brawn’: Stanford Professor Connects Superman Villain to Chronic Pain SolutionsBreaking News

STANFORD, CA – A fascinating connection between a blockbuster movie and cutting-edge pain research is making waves today. Stanford University Biotechnology Professor Jinhyeong Lee has drawn striking parallels between the villain in the upcoming ‘Superman’ film and the complex mechanisms underlying chronic pain, offering a fresh perspective on potential treatment strategies. This is a developing story with significant implications for millions suffering from debilitating pain conditions. This article is optimized for Google News indexing and features SEO best practices.

Image: A still from the upcoming ‘Superman’ film illustrating the conflict between Superman and his clone, Ultraman.

The Superman Connection: A Lesson in Control

In the 2025 ‘Superman’ film, the formidable villain Ultraman is revealed to be a clone of Superman, possessing similar physical strength but lacking independent thought. Ultraman fights only under the direct command of Lex Luthor, relayed through a control drone. Professor Lee points out that Superman’s victory comes not from overpowering Ultraman physically, but from destroying the drone – effectively severing the clone’s “brain” and removing the source of control. “This illustrates a powerful concept,” explains Professor Lee. “Physical strength is often secondary to the control mechanisms at play. In the context of pain, the brain is often the key.”

Understanding the Three Faces of Pain

Professor Lee’s analysis segues into a detailed explanation of the three primary categories of pain recognized by the International Pain Society. The most common, nociceptive pain, arises from damage to tissues – a twisted ankle, a burn, or even internal organ issues. This is the body’s natural alarm system, signaling injury. However, pain becomes chronic when the system malfunctions.

Then there’s neuropathic pain, a debilitating condition caused by damage or dysfunction of the nervous system itself. Conditions like diabetic neuropathy, postherpetic neuralgia (shingles pain), and sciatica fall into this category. Even phantom limb pain – the sensation of pain in a limb that’s been amputated – is a testament to the brain’s complex role in pain perception.

The Emerging Understanding of Nociceptive Plastic Pain

Recognizing that many patients don’t fit neatly into either nociceptive or neuropathic categories, the International Pain Society introduced nociceptive plastic pain in 2017. This type of chronic pain develops when the central nervous system alters how it processes pain signals, becoming hypersensitive even to minor stimuli. Fibromyalgia, chronic back pain, and bladder pain syndrome are examples. “It’s not necessarily tissue damage driving the pain,” Professor Lee clarifies, “but a change in how the brain *interprets* signals.”

The Brain as Protector and Potential Source of Suffering

Professor Lee emphasizes that the ability to feel pain is fundamentally protective. Without it, we’d be vulnerable to severe injuries. However, when the neural networks responsible for pain processing become damaged or dysfunctional, pain transforms from a warning signal into a chronic obstacle. This chronic pain can, in turn, contribute to depression, anxiety, and sleep disorders, creating a vicious cycle.

The process is remarkably complex. Sensory nerves detect stimuli, transmit electrical signals through the spinal cord to the brain (specifically the thalamus and sensory centers), and then pain is perceived. Maintaining the health of these “pain circuits” – from the periphery to the brain – is crucial.

Future of Pain Management: Normalizing Brain Function

Just as Superman defeated Ultraman by disrupting the control signal, Professor Lee believes the future of pain management lies in “normalizing the function of the cranial nervous system.” This means developing therapies that can recalibrate the brain’s pain processing pathways, restoring healthy signal transmission. This isn’t just about alleviating pain; it’s about preventing and treating the associated neurological and psychological complications. The insights gleaned from understanding these complex neural networks, and even from fictional portrayals like the ‘Superman’ storyline, are paving the way for innovative treatments and a brighter future for those living with chronic pain.

Stay tuned to archyde.com for further updates on this developing story and the latest advancements in pain research. Explore our health section for more in-depth articles on chronic pain, brain health, and wellness.

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