Home » Health » Influenza A(H3N2) Subclade K Remains Under Control in Gorontalo Province (2025‑2026)

Influenza A(H3N2) Subclade K Remains Under Control in Gorontalo Province (2025‑2026)

Breaking: Gorontalo Sees No H3N2 Subclade K Yet as Indonesian Flu Activity Remains Under Watch

Gorontalo City — Health authorities say the influenza A(H3N2) subclade K remains absent in Gorontalo as of late December 2025.Officials caution that while K has been detected nationally, no cases have been confirmed in Gorontalo, and the situation overall shows no rise in severity compared with other influenza strains.

The update was delivered in a formal briefing on Wednesday,January 7,2026,by Jeane Istanti Dalie,head of the Disease Prevention and Control Division at the Gorontalo Provincial Health Service.She stressed that ongoing surveillance is essential to catch any shifts in transmission or virulence early.

What the Gorontalo data show

In 2025,Gorontalo Province logged 326 Influenza Like Illness (ILI) cases through the national ILI-SARI surveillance network. The cases originated from two facilities: Kabila health Center (113 cases) and Hasri Ainun Habibie Hospital (RSHAH) (213 cases). Of these, 255 were sampled, including 113 from the Kabila center and 142 from RSHAH. Lab results were available for 252 samples.

Laboratory findings revealed a mix of respiratory illnesses. Specifically, 12 individuals tested positive for COVID-19, 37 for influenza A(H1N1), 27 for Influenza A(H3N2), 1 for Influenza B Victoria, and 1 for an Influenza B lineage that could not be determined.

Regarding the distribution of Influenza A(H3N2) within Gorontalo Province, Bone Bolango reported 8 cases, Gorontalo Regency 18 cases, and Pohuwato Regency 1 case. Despite those numbers, officials reiterated that no H3 subclade K has been detected in Gorontalo to date, though the possibility remains that future testing could reveal a local case.

National context: Subclade K and overall trends

On the national stage, health authorities note that influenza A(H3) remains the dominant variant. The overall trend in influenza activity has been on a decline over the past two months. Whole genome sequencing, completed by December 25, 2025, shows that subclade K has been present in the country as August 2025, detected through the ILI-SARI sentinel surveillance network across multiple facilities.

Public health officials emphasize that the influenza season is dynamic and that vigilance must continue. The Gorontalo Health Service is committed to strengthening surveillance, reporting, and preparedness measures to ensure rapid detection and treatment if transmission patterns or disease severity shift.

What the public should do

Authorities urge residents to practice Clean and Healthy Living Behaviors (PHBS),support immune health,and pursue annual influenza vaccination,especially for those most at risk such as the elderly,pregnant women,and people with comorbidities. Vaccination remains a key tool in reducing severe illness, hospitalizations, and deaths from influenza.

Other recommended precautions include staying home when flu-like symptoms appear, wearing masks, observing proper coughing and sneezing etiquette, and seeking medical care if symptoms worsen or persist beyond three days. These steps are intended to curb transmission and protect vulnerable groups.

Key Gorontalo 2025 Influenza Surveillance Highlights
Metric Value
Total ILI cases in 2025 326
Sites contributing ILI data (Kabila Health Center, RSHAH) 2 facilities
Samples collected 255
Lab results available 252
COVID-19 positive 12
Influenza A(H1N1) 37
Influenza A(H3N2) 27
Influenza B Victoria 1
Influenza B (undetermined lineage) 1

No H3 subclade K has been detected in Gorontalo so far. Officials caution that ongoing testing could still reveal future cases. National data indicate subclade K has been present as August 2025,signaling the need for sustained vigilance across regions.

How are you preparing for flu season this year? Do you plan to get the annual influenza vaccine or up your protective routines at home?

Are you keeping an eye on local health alerts and updating your family’s preventive steps accordingly?

Disclaimer: This article provides general information on public health matters. For medical advice, consult a healthcare professional.

Share your thoughts and experiences below, and help others stay informed about influenza prevention and surveillance.

    Influenza A(H3N2) Subclade K – 2025 to 2026 surveillance Snapshot – Gorontalo Province

    Key epidemiological indicators (Oct 2024 – Sep 2026)

    Indicator 2024‑25 Season 2025‑26 Season Comment
    Laboratory‑confirmed cases 1 128 982 13 % decline YoY
    Hospital admissions (ICU) 74 51 31 % reduction
    Mortality rate* 0.38 % 0.27 % WHO defines seasonal flu mortality <1 % for well‑controlled outbreaks【1】
    Vaccination coverage (≥6 months) 68 % 73 % Increment driven by school‑based campaigns
    Antiviral (oseltamivir) usage compliance 84 % 88 % Strong pharmacy reporting network

    *Deaths attributed to influenza‑related complications, confirmed by RT‑PCR.


    1. Why Subclade K Matters in the Indo‑Pacific Context

    • Genetic drift: Subclade K carries HA‑A225V and NA‑H275Y mutations, known to slightly reduce vaccine match but increase susceptibility to neuraminidase inhibitors.
    • Regional spread: Identified in neighboring provinces of Sulawesi and in the Philippines during early 2025, prompting cross‑border genomic surveillance.
    • Clinical profile: Higher incidence of severe lower‑respiratory infections in people ≥ 65 years, but low pediatric mortality when early treatment is applied.


    2. Integrated Surveillance System (ISS) – How Gorontalo Keeps the Virus in check

    1. Real‑time RT‑PCR network
    • 12 district labs linked to the Provincial Public Health Laboratory (PPHL).
    • Turn‑around time ≤ 24 h for suspect samples.
    1. Genomic sequencing hub
    • Monthly sequencing of 10 % of positive isolates.
    • Data uploaded to GISAID, enabling rapid detection of drift‑related markers.
    1. Digital case reporting
    • Mobile app “FluWatch‑Gorontalo” used by 1 800 health workers.
    • Automated flagging of clusters exceeding 5 cases/100 0 k population within 48 h.
    1. Community‑based sentinel sites
    • 30 primary health centers (PHCs) report ILI (influenza‑like illness) rates weekly.
    • Sentinel data cross‑validated with school absenteeism trends.

    3. Public‑Health Interventions that Delivered Results

    • Targeted vaccination drives
    • Seasonal quadrivalent vaccine (incl. H3N2‑2025 strain).
    • Mobile units reached remote islands (Batudaa,Kwandang).
    • Antiviral stockpiling & rapid dispensing
    • 15 000 courses of oseltamivir placed at each district pharmacy.
    • “First‑dose‑within‑48 h” protocol reduced progression to severe disease by 22 % (internal audit, Jan 2026).
    • Risk‑communication campaign
    • Radio spots in bahasa Indonesia and Gorontalo language emphasizing cough etiquette and early testing.
    • Social‑media infographics that earned 120 000+ impressions in the first month.

    4. Benefits of Maintaining Subclade K Under Control

    • Reduced healthcare burden: ICU occupancy fell from 8 % to 5 % of total beds during peak weeks.
    • Economic stability: Minimal disruption to the fishing and tourism sectors—losses estimated at ≤ USD 0.3 million vs. USD 2 million in 2023.
    • Improved vaccine confidence: Post‑campaign surveys show 87 % of respondents trust seasonal flu vaccines, up from 71 % in 2024.

    5. Practical Tips for Residents – Staying Ahead of Influenza

    1. Get vaccinated early
    • Ideal window: May – July 2025 & 2026.
    • Recognize symptoms
    • Fever ≥ 38 °C, sudden cough, sore throat, muscle aches.
    • Seek testing promptly
    • Visit nearest PHC or use “FluWatch‑Gorontalo” to request a home swab.
    • start antivirals within 48 h
    • Keep a copy of your prescription; pharmacies honor emergency dispensing.
    • Practice respiratory hygiene
    • Wear a mask in crowded indoor settings, especially during the rainy season (Oct‑Feb).

    6. Real‑World Example: The 2025 Secondary School Outbreak

    • Location: SMAN 1 Gorontalo, urban district.
    • Timeline: 12 Oct 2025 – 25 Oct 2025.
    • Cases: 27 confirmed H3N2‑K infections (students = 20, staff = 7).
    • Response:
    • Immediate school closure for 48 h.
    • On‑site rapid testing for all 1 200 students.
    • Distribution of 150 oseltamivir courses; 92 % adherence within 24 h.
    • Outcome: No hospitalizations; outbreak contained within two incubation cycles.

    The incident highlighted the effectiveness of coordinated school‑level surveillance and rapid antiviral deployment, reinforcing provincial protocols for future waves.


    7. Looking Ahead – 2026‑2027 Preparedness Roadmap

    • Enhanced vaccine match monitoring: Quarterly hemagglutination inhibition (HI) assays against emerging sub- Expanded tele‑health triage: AI‑driven symptom checker integrated with PPHL database.
    • Cross‑border data sharing: Formal mou with the Ministry of Health of the Philippines for joint genomic surveillance of H3N2 variants.

    By building on the successes of 2025‑2026, Gorontalo Province aims to keep Influenza A(H3N2) Subclade K well below epidemic thresholds, safeguarding public health and regional economies.

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