Minimally invasive adrenalectomy, a surgical procedure to remove the adrenal gland, is evolving with the increasing adoption of robotic assistance. A recent analysis indicates that robotic adrenalectomy (RA) offers comparable safety to the traditional laparoscopic approach (LA) while potentially shortening hospital stays, despite requiring longer operating times. This development is particularly relevant for patients undergoing procedures in specialized endocrine surgery centers.
The adrenal glands, located above the kidneys, produce hormones essential for regulating various bodily functions. Adrenalectomy is often necessary to treat tumors, hormone imbalances, or other adrenal gland diseases. Traditionally, laparoscopic adrenalectomy has been the standard minimally invasive technique. Although, robotic surgery, with its enhanced precision and dexterity, is gaining traction as a viable alternative. A study published in January 2026 compared outcomes between robotic and laparoscopic adrenalectomy, analyzing data from a high-volume tertiary endocrine surgery center.
Shorter Stays, Longer Operations: A Comparative Analysis
Researchers retrospectively analyzed data from 181 patients who underwent minimally invasive adrenalectomy between June 2020 and September 2025, comparing 126 who had laparoscopic procedures with 55 who underwent robotic-assisted surgery. The findings, published in J Robot Surg, revealed a statistically significant difference in the length of hospital stay, with patients in the RA group being discharged sooner (p = 0.019). However, the operative time was significantly longer for the robotic group (p < 0.001).
Importantly, the study found no significant differences between the two techniques regarding complications, the need for blood transfusions, or conversion rates to open surgery (all p > 0.05). This suggests that robotic adrenalectomy is a safe procedure with a complication profile similar to that of laparoscopy. Further analysis, stratified by the location of the adrenal gland (laterality), consistently showed longer operative times with robotic assistance for both right- and left-sided procedures (p = 0.001 and p < 0.001, respectively). Multivariate analysis indicated that the surgical approach and tumor diameter were the primary independent factors affecting operative time (both p < 0.001).
Expanding Options in Endocrine Surgery
The increasing acceptance of both laparoscopic and robotic adrenalectomy reflects a broader trend toward minimally invasive approaches for adrenal gland disease. Experience from a tertiary center highlights the growing role of these techniques, particularly for benign adrenal lesions. A five-year comparative study reinforces the feasibility of robotic adrenalectomy in high-volume centers.
While robotic adrenalectomy requires a longer time in the operating room, the potential benefit of a shorter hospital stay could be significant for patients, reducing healthcare costs and improving recovery. The ergonomic advantages of robotic surgery may also contribute to improved surgeon comfort and potentially enhance precision, although this was not directly assessed in the study. Initial experiences with robotic-assisted laparoscopic adrenalectomy in tertiary centers, as reported in Cureus, further support the procedure’s feasibility and positive perioperative outcomes.
Looking ahead, continued research and refinement of robotic techniques will be crucial to optimize operative times and further define the role of robotic adrenalectomy in the management of adrenal gland disease. As more surgeons gain experience with the technology and as robotic systems continue to evolve, it is likely that robotic adrenalectomy will develop into an increasingly common and valuable tool in the endocrine surgeon’s armamentarium.
This information is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.
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