The American Medical Association (AMA) is collaborating with a leading public health research group to establish an independent system for reviewing vaccine safety, and effectiveness. This move comes amid growing concerns and significant restructuring within the Centers for Disease Control and Prevention (CDC), raising questions about the future of vaccine recommendations and public trust in immunization programs.
The partnership aims to replicate, and potentially expand upon, the role historically held by the CDC’s Advisory Committee on Immunization Practices (ACIP). ACIP, established in 1964, has long been responsible for advising the CDC on how vaccines approved by the Food and Drug Administration should be utilized. However, recent changes, including the removal of ACIP members and the disinvitation of experts from organizations like the AMA and the American Academy of Pediatrics, have prompted the AMA to grab action. This initiative seeks to provide a robust, independent assessment of vaccine data and guidance, ensuring continued confidence in these critical public health tools.
CDC Restructuring and Concerns Over Independence
Over the past year, the CDC has undergone substantial changes that have sparked alarm among public health experts. In June 2025, the agency informed several major medical organizations that their experts would no longer be involved in the workgroups that form the foundation of ACIP. According to reporting from the Associated Press, the CDC stated these organizations were considered “special interest groups” and therefore presumed to have a “bias” based on their constituencies. This decision, as reported by the Associated Press, has raised fears of fragmentation in vaccine guidance, potentially leading to conflicting recommendations from the government and healthcare providers.
The AMA has consistently voiced its concerns regarding these developments. Statements released throughout 2025, as documented on the AMA website, highlight the organization’s opposition to actions perceived as undermining the integrity of the vaccine recommendation process. These include opposition to Florida’s plan to end vaccine mandates in September 2025, and statements regarding changes to the CDC website on autism and vaccines in November 2025. The AMA also issued a joint statement with 79 medical societies in June 2025 backing vaccination against respiratory viruses.
A New System for Vaccine Review
Details of the new review system being developed by the AMA and its partner are still emerging. However, the goal is to create a transparent and evidence-based process for evaluating vaccine safety and effectiveness. This will involve a comprehensive review of scientific literature, data analysis, and input from a diverse group of experts. The AMA launched vaccine infographics for patients and physicians in September 2025, signaling a commitment to improving public understanding of vaccine science.
The move also follows a period of internal turmoil at the CDC, including leadership changes, as noted in an August 2025 AMA statement. These events, coupled with the changes to ACIP’s composition and the exclusion of key medical organizations, have fueled concerns about political interference and a potential erosion of public trust in the CDC’s recommendations. The AMA’s independent review system is intended to address these concerns and provide a reliable source of information for both healthcare professionals and the public.
Looking Ahead
The launch of this independent vaccine review system represents a significant step in safeguarding the integrity of vaccine recommendations. As the CDC continues to navigate its internal restructuring, the AMA’s initiative will likely play an increasingly important role in ensuring that vaccine policies are grounded in sound science and free from undue influence. On February 17, 2026, Medical Xpress reported that the AMA’s launch of this review system comes after major changes at the CDC have raised alarms among experts.
The success of this effort will depend on its ability to maintain transparency, attract qualified experts, and build trust with the public. It remains to be seen how the CDC will respond to this independent initiative and whether the two organizations will be able to collaborate effectively in the future.
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Disclaimer: This article provides informational content only and is not intended to be a substitute for professional medical advice. Always consult with a qualified healthcare provider for any questions you may have regarding your health or treatment.