2023-04-27 06:15:52
The National Health Organization has confirmed that there is no monkeypox vaccine in the country.
The first case of monkeypox was reported in Pakistan. On April 25, the National Institute of Health Islamabad confirmed monkeypox in a person deported from Saudi Arabia. has been done, all measures to prevent diseases have been ensured.
Juarez City.- The Ministry of Health urges citizens to carry out preventive measures to prevent monkeypox from being transmitted between people.
In a statement issued by the state government, the deputy director of Epidemiology, Gumaro Barrios Gallegos, indicated that it is an infectious disease originating in Central African countries, and Mexico maintains epidemiological surveillance of cases.
He mentioned that people who have traveled to other regions where cases have occurred should be attentive to the presence of any symptoms, since transmission occurs through direct contact with someone who is sick, usually with lesions generated on the skin or contact with personal items.
The epidemiologist commented that the incubation period of the virus ranges from 5 to 21 days, in which some clinical picture can manifest.
As part of the symptoms, in the first days, fever over 38º C, headache, swollen lymph nodes, back and muscle pain, as well as discomfort or fatigue appear.
Also in the first three days, following the onset of fever, skin lesions appear on the face and the rest of the body, ranging from the macula, papule, vesicle and blister to form scabs.
At the state level, 20 confirmed cases are registered, of which 10 cases correspond to the municipality of Chihuahua, 9 in the municipality of Juárez and one case in the municipality of Camargo.
It is worth mentioning that 15 people have recovered from this condition, and of the total cases studied there is a record of 16 negatives.
The deputy director urged to continue with preventive measures to avoid transmission, which include not having close contact with sick people, since the virus is transmitted through skin lesions, body fluids or inhaling respiratory droplets, which They are expelled by talking, coughing or sneezing.
He added that it is important that whoever has symptoms must remain in isolation, in addition to using a face mask, washing hands frequently or using antibacterial gel, applying respiratory etiquette measures when coughing or sneezing, cleaning personal areas and objects, as well as keep a healthy distance.
Emphasis was made that for those who travel to other regions where cases are reported, the presence of any mentioned symptom should be monitored, during the period of 5 to 21 days following their return.
Until recently, Mpox virus was only found in certain parts of Africa when humans became infected through contact with wild animals. However, in May 2022, for the first time, a major outbreak took place outside of Africa; the viruses spread solely through human-to-human transmission. This ongoing outbreak has so far reached more than 100 countries and has been classified by the World Health Organization as a Public Health Emergency of International Concern. The cases of the disease differed from previous outbreaks not only in the way they were transmitted, but also in the symptoms of the disease. These differences in virus behavior raised concerns that the currently circulating monkeypox viruses had changed to the point where they were no longer responsive to available drugs.
“We were really concerned that the virus might have evolved in a way that made it resistant to current therapies. Fortunately, this is not the case,” said study author Prof. Jindrich Cinatl from the Institute for Medical Virology, Goethe University Frankfurt/University Hospital Frankfurt. The research team isolated Mpox viruses from twelve patients in the current outbreak and multiplied them in cell cultures. The isolates were then tested for susceptibility to three available drugs used to treat: tecovirimate, cidofovir and brincidofovir. Results showed that all 12 isolates continued to respond to treatment with clinically achievable concentrations of commonly used drugs.
The mpox virus is closely related to the smallpox virus (variola virus), which caused large outbreaks with high death rates until it was eradicated by vaccination in the late 1970s. While smallpox, now eradicated, caused a very severe disease with a mortality rate of regarding 30 percent, mpox is a milder disease. Despite this, the death rate is still around three percent.
After examining samples from “high-risk contacts”, the ITM concludes that people infected with the virus can transmit it even before showing symptoms. “This is an important explanation for the spread of the virus,” the institute says.
In Belgium and the rest of Europe, the monkeypox epidemic is nevertheless on the decline. “Since the first case identified in May, we have learned that the Mpox virus is transmissible without necessarily showing symptoms,” explains Koen Vercauteren from the clinical virology department at IMT. “We have now demonstrated that infected people can pass on the virus even before symptoms appear.”
The institute’s research team analyzed 25 high-risk contacts. Sexual partners and roommates of infected people took daily samples that the laboratory assessed. Participants also kept diaries and were closely monitored by physicians.
“PCR test results prove they were potentially infectious up to four days before they tested positive,” Vercauteren adds. “The risk of contamination through sexual contact is also much higher than what we have assumed until now. On the other hand, it is very low during non-sexual contact. And although skin lesions are one of the specificities of the disease, they are less frequent than we supposed.”