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Breaking: Panama Reports No Influenza A(H3N2) Subclade K Cases While the Variant Spreads Across the Northern Hemisphere
Panama’s Ministry of Health (Minsa) issued a preventive epidemiological alert on December 13, 2025 after the Pan American Health Organization (PAHO) warned of an early and intense 2025‑2026 flu season in the northern hemisphere. The alert highlights the rapid circulation of influenza A(H3N2) subclade K in north America and europe, but confirms that no confirmed cases of this variant have been detected in Panama.
Current Situation in Panama
- Flu activity remains low: 21.6 cases per 100,000 inhabitants.
- Pneumonia & bronchopneumonia: 9.2 per 100,000.
- Bronchiolitis is declining, now at 11 per 100,000.
- Laboratory positivity rates – Influenza: 32.6 %; RSV: 24 %; SARS‑CoV‑2: 0.4 %.
- Total influenza‑related deaths this year: 97; COVID‑19 deaths: 47.
What Is Subclade K?
Dr. Xavier Sáez‑Llorens, head of research at the Dr. José Renán Esquivel Children’s Hospital,explains that subclade K is a natural mutation of the traditional H3N2 strain. It carries genes that increase transmissibility and grant modest immune‑escape capabilities, but it does not make the virus more lethal.
Regional Comparison
| Region | Dominant flu Subtype | Subclade K Presence | current Flu activity (per 100k) |
|---|---|---|---|
| North America (US & Canada) | A(H3N2) – subclade K | High | ≈ 35‑40 |
| Europe (UK, Spain, Germany) | A(H3N2) – subclade K | High | ≈ 30‑38 |
| Caribbean & Central America | A(H1N1)pdm09 | Low/Absent | ≈ 22 |
| panama | Mixed (A(H3N2) traditional, A(H1N1), B, RSV, SARS‑CoV‑2) | None detected | 21.6 |
Why Panama’s Numbers Remain Low
Panama is transitioning into its dry season, a period that historically suppresses influenza transmission. The country’s robust surveillance network continues to monitor respiratory syndromes, ensuring any uptick is caught early.
vaccination Still Works
despite genetic drift, the current quadrivalent flu vaccine retains strong protection against severe disease, hospitalizations, and death. Health officials urge everyone-especially young children, seniors, pregnant women, and those with chronic conditions-to get vaccinated.
Travel Advice for the Northern‑Hemisphere Season
- Check vaccination status before departure.
- Receive the flu shot at least two weeks prior to travel.
- If more than four to six months have passed as your last dose, consider a booster.
- Use masks in crowded indoor settings and practice frequent hand hygiene.
- Upon return, self‑isolate and wear a mask if respiratory symptoms develop; notify health services of recent travel.
What’s Next?
The Minsa’s Department of Epidemiology will keep “permanent monitoring” of respiratory viruses and issue updates as the situation evolves. No increase in case severity has been recorded, and the latest epidemiological week (48) reported zero new influenza‑ or COVID‑related deaths.
Further Reading
- CDC – 2024‑2025 Flu Season Overview
- World Health Organization – Influenza Updates
- PAHO – Influenza Surveillance
Reader Engagement
do you plan to get a flu booster before traveling abroad this winter? How has your experience with the flu vaccine changed over the past few seasons?