How Danish laboratories got a head start in their ecological transition

2023-12-14 10:30:00 They are one step ahead and want to make it known. The Danish laboratories established industrially in France, Novo Nordisk, Coloplast, Leo Pharma, Lundbeck and ALK Pharma, form the Franco-Danish Health Alliance. An association intended to bring together manufacturers who share a solid industrial installation in France, since these laboratories represent 4,000 employees … Read more

En bref: Vertex, Sandoz, Naobios, Pfizer

2023-12-15 15:00:00 Vertex signs licensing agreement with Editas Medicine Vertex has just signed a licensing agreement with the American biotech Editas Medicine for its Cas9 gene editing technology, CRISPR scissors. This agreement includes Casgevy (exagamglogene autotemcel), a cell therapy from Vertex approved in early December by the FDA against sickle cell disease. Thanks to this … Read more

Merck fails in phase III against multiple sclerosis

2023-12-11 13:00:00 Merck KGaA provided an update on phase III studies evaluating evobrutinib for the treatment of relapsing multiple sclerosis (MS). Neither trial met its primary endpoints. Among these criteria, the reduction in annualized relapse rates compared to oral teriflunomide, the reference treatment. “With evobrutinib, our goal was to address the significant unmet need in … Read more

The Telethon between first medical victories and 95% of rare diseases still without treatment

2023-12-08 07:00:00 «20 years ago we only talked about tragedies and deaths», recalls Laurence Tiennot-Herment when she took over as president of the AFM-Téléthon. Since 2018, she has been delighted “a real acceleration of results and victories“. Thanks to donations, Généthon, the association’s laboratory, has enabled revolutionary breakthroughs in the understanding and even treatment of … Read more

CDMOs, collateral victims of disaffection for the Covid-19 vaccine?

2023-12-01 07:55:00 What remains of the unprecedented production effort launched during the Covid-19 pandemic? In 2021, CDMOs benefited from an unprecedented spotlight during the health crisis, with the production of the mRNA vaccine. Two years later, the record volumes requested to cope with the massive vaccination campaigns fizzled out. And push subcontractors to adapt. Latest … Read more

In the pipelines: Sanofi, Valneva, GSK

2023-12-01 08:00:00 Dupixent effective against BCPO Sanofi released new data on its blockbuster drug Dupicent (dupilumab), evaluated in a second phase III trial against chronic obstructive pulmonary disease (COPD). These results confirm those of the first study, with a 34% reduction in disease exacerbations. As a result, filing a Supplemental Biologics License Application (sBLA) with … Read more