The Link Between Metacarpal Bone Crushing and Heart Disease: Unveiling the Role of Protein Misfolding and Amyloidosis

2023-08-03 12:20:07

How the crushing of the metacarpal bone is related to the heart disease is still unclear. A possible trigger for both might be a misfolding of a protein (amyloidosis). Previous studies had shown that the misfolding of the serum transport protein transthyretin (transthyretin amyloidosis, ATTR) and its deposition is a risk factor for cardiac insufficiency. About half of all amyloidosis patients have had carpal tunnel syndrome in the past. In a further analysis, the team found that amyloidosis was found in 0.06 percent of patients with carpal tunnel syndrome and 0.02 percent of the control group.

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#Carpal #tunnel #syndrome #heart #failure

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