They get paraplegic mice to walk again

Madrid

Updated:01/22/2021 14:25h

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German researchers have succeeded in getting mice paralyzed due to spinal cord injury to walk again, reestablishing a neural link hitherto considered irreparable in mammals by using a designer protein injected into the brain.

Spinal cord injuries in humans, caused by sports or traffic accidents, produce paralysis because it affects the ability of the nerve fibers that carry information between the muscles and the brain to regenerate.

Until now, they have been considered absolutely irreparable. When nerve fibers called axons – responsible for transferring information from the brain to the muscles and vice versa – are damaged, communication is interrupted and cannot be restored.

The novelty of our study is that the protein is not only used to stimulate the nerve cells that produce it, but is also transported through the brain

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