A “painting” brushed on our soul, the trace of the “Seal that the ring imprints on the wax” … In his Treatise on memory and reminiscence, Aristotle answered in images to an already old question: how are our memories stored in our brain? And where could these engrams, biological traces left in our mind by our memories, be hidden? The hypotheses were numerous, and their proliferation did not slow down with the advent of neuroscience. “At one time, we talked about the” grandmother neuron “”, laughs Benoît Delatour, neuroscience researcher at the Brain Institute (ICM, Paris), specialist in Alzheimer’s disease and prion diseases.
A slightly mocking name, to evoke the idea that we would have populations of neurons exclusively devoted to recognizing, for example, the face of our grandmother … “We also thought that the engram could consist of specific proteins, continues Benoît Delatour. Then a whole