Chronic itch, defined as itching lasting longer than six weeks, is a common complaint encountered in dermatology clinics. However, many individuals don’t seek medical attention for persistent itching, making the true prevalence of this condition difficult to ascertain. New research is focusing on understanding how often chronic itch occurs in older adults, who is most at risk, and how it impacts their overall quality of life. This growing area of study highlights the necessitate to “appear beyond the skin” when addressing persistent itch in an aging population.
“Chronic itch occurs at all ages, but we see it relatively frequently in older adults,” explains Dr. Juliette Bollemeijer, a physician-researcher at Erasmus MC in Rotterdam. “This is linked to multiple changes that occur with aging. The skin barrier function declines, leading to drier skin. Simultaneously, the immune system changes – it doesn’t necessarily become less active, but less effective, resulting in a persistent, low-grade inflammatory response. The nervous system also ages. Together, these changes can make older adults more susceptible to itch.”
Prevalence of Chronic Itch in Older Adults
A recent study, utilizing data from the ongoing Rotterdam Study – a large-scale epidemiological study that began in 1990 in the Ommoord district of Rotterdam – revealed a significant prevalence of chronic itch among older individuals. Researchers found that nearly 1 in 10 older adults experience chronic itch. The study involved 4,474 participants and used comprehensive questionnaires to assess the presence and impact of persistent itching. This research, conducted as part of Dr. Bollemeijer’s doctoral research, provides valuable insights into the scope of the problem within the general population.
The Rotterdam Study, also known as the ERGO-onderzoek, provides a robust dataset for investigating health concerns in an aging population. As detailed in a 2025 publication in ERJ Open Research, Dr. Bollemeijer and her colleagues investigated both chronic cough and chronic pruritus (itch) in older adults.
The Aging Body and Itch: A Complex Relationship
The development of chronic itch in older adults isn’t simply a matter of dry skin. The interplay between the skin, immune system, and nervous system is crucial. As the skin’s protective barrier weakens, it becomes more vulnerable to irritants, and allergens. The altered immune response can lead to chronic inflammation, even in the absence of obvious skin conditions. Changes in the nervous system can amplify itch sensations and make them more difficult to ignore. According to DOQ, a platform for healthcare professionals, understanding these complex interactions is key to effective management.
Impact on Quality of Life
Chronic itch isn’t merely a nuisance. it can significantly diminish an individual’s quality of life. Persistent itching can disrupt sleep, leading to fatigue and daytime drowsiness. It can also cause anxiety, depression, and social isolation. The constant urge to scratch can lead to skin damage, increasing the risk of infection. Dr. Bollemeijer’s research emphasizes the importance of recognizing the broader impact of chronic itch on the well-being of older adults.
Juliette Bollemeijer, MD, PhD candidate at Erasmus MC, is actively researching pruritus and its impact on older adults. Her LinkedIn profile details her experience and research interests. She also has a profile on the Erasmus University Rotterdam website, showcasing her research output, including a recent article on chronic pruritus in older adults published in Acta Dermato-Venereologica.
Looking ahead, further research is needed to identify the underlying causes of chronic itch in older adults and to develop more effective treatments. A deeper understanding of the interplay between skin health, immune function, and neurological changes will be crucial for improving the lives of those affected by this often-debilitating condition. Continued investigation into the prevalence, risk factors, and impact of chronic itch will help healthcare professionals provide more targeted and compassionate care.
Have you or a loved one experienced chronic itch? Share your thoughts and experiences in the comments below.
Disclaimer: This article provides informational content and should not be considered medical advice. Please consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.
