world ACE inhibitors have no particular corona risk

ACE inhibitors have no particular corona risk

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FRecent warnings in the media have caused considerable uncertainty that common remedies for high blood pressure could promote infection with the new coronavirus Sars-CoV-19 and favor severe pneumonia among those infected. We are talking about ACE inhibitors and angiotensin antagonists, drugs that lower blood pressure and relieve the heart by switching off the vasoconstricting hormone angiotensin in different ways.

The media shock waves were triggered by theoretical considerations, not by the results of scientific studies. Scientists led by Michael Roth from the University Hospital Basel in the journal “Lancet” had given reason to think that the said blood pressure lowerers led to an increase in the protein that Sars-CoV-19 uses to infect its host. The viral “robber ladder” is an enzyme called ACE2, which is found on the surface of many cells and has the task of incapacitating angiotensin. As an opponent of the angiotensin-producing enzyme ACE, ACE2 thus supports the therapeutic effects of ACE inhibitors and angiotensin antagonists.

So far, it has not been possible to prove whether the aforementioned blood pressure lowerers actually help the new type of corona virus. The Lancet authors nevertheless believe that this is possible. As an indication of such a danger, they argue that patients with severe Covid 19 course often have high blood pressure and other disorders that are often treated with ACE inhibitors and angiotensin antagonists.

Do corona patients benefit from ACE inhibitors?

Franz Messerli from the Department of Cardiology at the University Hospital in Bern does not accept this argument. As the high-pressure expert says on request, the virus is known to particularly affect old and sick people. With age, however, the risk of high blood pressure and many other ailments also increases. It is therefore not surprising that patients with a severe Covid 19 course are more often affected by such conditions.

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