Advances in the treatment of early breast cancer that are hormone receptor (HR) positive and human epidermal growth factor receptor (HER2) negative are held at Ballroom 3, Grand Hotel. Hyatt Erawan Bangkok, led by Dr. Shahina Dawood, a specialist physician and cancer consultant from Mediclinic Middle East, UAE, together with Prof. Dr. Pornchai Ocharoenrat, M.D., a breast cancer specialist. Head of the Breast Center Med Park Hospital and breast cancer surgeon Chaophya Hospital convey direct experience After having been diagnosed with breast cancer and take time to heal
Breast cancer is currently the most common type of cancer in women and HR+ HER2 breast cancer is the most common subtype, according to the American Cancer Society, accounting for 1 in 8 women diagnosed with breast cancer at some point in their lives. stage of breast cancer Several risk factors include family history, age, personal health history. and choice of life Although there is no sure way to prevent breast cancer. But there are things you can do to reduce the risk. These include maintaining a healthy weight. exercise regularly eat healthy food limit alcohol consumption It’s important to remember that there is hope. with advances in treatment Breast cancer survival rates are steadily increasing. Today, more than 80% of women diagnosed with early breast cancer will survive at least 5 years, and more than 60% of women diagnosed with breast cancer will survive at least five years. that it is the last stage of breast cancer that will survive for at least 5 years. and proper treatment Your chances of surviving breast cancer are better than ever.
According to data in 2020, there are about 18,000 new cases per year, or 49 per day, and about 4,800 deaths from breast cancer, or about 13 per day. 70% of all breast cancers are HR+, HER2. The diagnosis of HR+, HER2- breast cancer is often detected at an early stage. which tends to increase the incidence of the disease steadily It is estimated that in the year 2023, approximately 22,000 new cases of breast cancer will be found. However, 90 percent of breast cancer can be diagnosed in the early stages, 70 percent of which are usually the type that has a positive effect on hormone receptors Early breast cancer treatment It consists of surgical removal of the lump. by a specialist doctor and/or in conjunction with adjuvant treatment according to the risk factors of each patient, such as the stage of the disease, biomolecular information according to abnormal gene expression in cancer cells abnormal levels of certain proteins in cancer cells Including the patient’s physical factors and other laboratory tests. which the treatment usually consists of Hormone therapy, chemotherapy, radiotherapy, and targeted therapy, where medical professionals will consider individual patient risks and decide on treatment according to standard guidelines.
Once diagnosed with breast cancer There are different treatment approaches. It depends on the stage and type of cancer. In addition to the type of cancer staging of the disease Three sections of information are required: 1. The size of the tumor measured by the largest lump, 2. The spread of the cancer to the lymph nodes, and 3. The spread of the cancer to other organs.
However, after obtaining all 3 preliminary information will know what stage cancer is There are cancer stages 0-4, with treatment depending on the stage of the disease, consisting of: The chance of spreading to the lymph nodes is only 1-2%. If properly treated, the chance of being cured is more than 98%. The main treatment for this stage of cancer is surgery and 2. Early breast cancer (stages 1 and 2) breast cancer. At this stage, the cancer is less than 5 cm in size and has not spread to the lymph nodes. or has spread to no more than 3 glands and has not spread to other organs treatment of breast cancer at this stage The main treatment is surgery. Other treatments are complementary treatments such as chemotherapy, radiation, targeted drugs, and anti-hormonal drugs. The doctor will use the disease stage information together with the type of disease. come up with a treatment plan The type of disease was known from a special biopsy stain. To classify cancer types, including Staining of estrogen receptor (ER), progesterone receptor (PgR), HERTU cancer gene (HER2)
For the ultimate goal of early breast cancer treatment is Preventing Cancer from Recurring and spread Including helping patients live longer. However, it was found that more than 20% of patients often recur and may lead to metastatic cancer that cannot be cured. and cause death later 1 Patients with recurrent disease and metastases It usually occurs within 2-3 years after being fully diagnosed and treated. Especially in early breast cancer patients who are at high risk. The co-factors associated with a high risk of recurrence consisted of 2,3: 1. Detection of cancer cells in the lymph nodes. 2. Large tumor size more than 5 cm. 3. Grade 3 severity of cancer cells. 4. High rate of cell division and growth
In the past, hormonal adjuvant therapy, for about 5 years, has been standard therapy in patients with early hormone receptor-positive breast cancer. At present, adjuvant therapy with hormonal drugs combined with targeted therapy in patients at high risk of recurrence can reduce the risk of recurrence and metastases6.