Anan reveals the results of Hong Kong’s research, a cross-vaccination formula, 3 injections, creates a real high immunity. but can still get infected with covid
On August 30, Dr. Anan Chongkaewwatana, a virologist Director of Animal Health and Management Innovation Research Group National Center for Genetic Engineering and Biotechnology (Biotech) Facebook post Anan Jongkaewwattana
If you still remember the past March Hong Kong has been hit hard by the BA.2 outbreak, with estimates that the number of infections in the country could exceed 50% of the population. During the same period, a research team at the University of Hongkong conducted a comparative study of the efficacy of the booster vaccine in the country’s population. fit Since Hong Kong has only two vaccines, CoronaVac (Sinovac) and Pfizer mRNA, the group receiving the first two doses will have only CC (Sinivac x2) and BB (Pfizer x2). to receive a 3rd dose vaccine, which may be CoronaVac or Pfizer, which made the study into 4 groups: CC-C (Sinovac x3), CC-B (Sinovac x2, 3 Pfizer), BB-C (Pfizer x2, 3 Stimulated with Sinivac) and BB-B (Pfizer x3)
In laboratory tests to ascertain immunity against real viruses, the BB-B and CC-B groups showed the highest viral suppression antibody values in all groups. However, omicron viruses BA.1, BA.2 showed less inhibition. More than 10 times lower than the original strain of the CoronaVac-activated group, no matter what the first 2 injections were given. It appears unable to activate antibodies against BA.1 and BA.2 at all. The effect of antibodies that suppress the virus in the lab clearly shows that the mRNA vaccine is more effective. but interesting is The research team also took the samples to look at T cells. It was found that T cells in the group that had been injected with CoronaVac before and then stimulated with CoronaVac or Pfizer had a detectable change which was higher within 7 days, but the group who had been injected with Pfizer and stimulated returned. No changes were found in T cells, which is interesting. The proteins that the inactivated virus makes the body see may be what T cells see.than
The most interesting point of this work is that Each group of volunteers who received the vaccine had to go through a major outbreak in the country in March. The research team found that 59 people had contracted the coronavirus and divided them among different groups. The numbers, when analyzed, showed that the CC group, whether stimulated by CoronaVac or Pfizer, were equally infected with COVID. Although the antibody value of the CC-B group was higher than CC-C, it was at a level that not enough to prevent infection People who were stimulated by Pfizer, but if you look at the actual % in the Y axis, the BB-B group looks different from CC-C and CC-B as well, only the BB-C group may be higher than the others.
This research looked at the number of infected patients. but not distinguishing the severity of symptoms Haven’t seen the picture yet. Is there any difference between the groups or not?