Apple Watch is helping research into cancer treatment, atrial fibrillation, and heart rhythm health for firefighters in the US and Europe

Do you know what is the normal heart rate for an average healthy adult in a day? The answer is 100,000 times.The frequency of heart beating is actually closely related to health. Apple Watch with mobile phoneApple Watch App, through the high and low heart rate notification, cardiac fitness level, arrhythmia notification and ECG app, you can check whether you have atrial fibrillation (AFib) and other heart health conditions.

The “ECG” app currently supports the electronic heart rate sensor on Apple Watch Series 4, Series 5, Series 6, Series 7, Series 8 or Ultra to record your heartbeat and heart rate, just confirmApple Watch wear it snugly on yourApple Watch on the wrist selected in the app.then inApple Watch open onelectrocardiogram”App. Then place your arms on the table or on your lap. Using your free hand, place your finger on the Digital Crown. After a while, you can know your ECG.

However, the practical application is not limited to this. According to the latest report released by Apple, Apple Watch is checking the health of front-line personnel. To further advance discoveries that improve health at scale, Apple has launched the Investigator Support Program. Through the program, Apple is providing researchers with the Apple Watch device to use the Apple Watch to study the heart in ways never before possible.

Toxicity Study Associated with Childhood Cancer Treatment Using the Apple Watch ECG App

Associate Professor Rachel Conyers and Dr Claudia Toro are senior pediatric oncologists from Melbourne, Australia, caring for children primarily in tertiary pediatric oncology clinics and conducting toxicity studies related to childhood cancer treatment at the Murdoch Children’s Research Institute. Together, they study the effect of therapy on heart rhythm and try to find innovative interventions. It is the patients who inspire their research, stories of success and heartbreak.

Toxicity in cancer treatment leads to various cardiac arrhythmias, such as the potentially life-threatening long QT syndrome. Long QT syndrome causes an irregular heartbeat that prolongs the time it takes for blood to flow through the heart. Because of the predisposition to long QT, children treated for cancer typically have screening 12-lead ECGs at least once a week, Dr. Conyers said. However, outpatients also need a way to monitor heart rate.

“I read the Apple Heart Study and thought it might be important in pediatrics,” Dr. Conyers said. “We used to think that cardiotoxicity was a 10-year post-treatment thing. But now we know that new cancer therapies like specific inhibitors or immunotherapy) can cause cardiac arrhythmia within 48 hours of taking the drug, so there is a big gap between what we know about toxicity and what actually happens.”

In the coming months, Dr. Conyers and her team at the Murdoch Children’s Research Institute will begin studying the sensitivity of the Apple Watch ECG app with 40 children and adolescent patients. The team will use this as a starting point to find ways to allow patients to take an ECG anytime, anywhere. With these analyses, the team hopes to better understand the reality of cardiotoxicity and identify potential opportunities for intervention.

Detecting firefighters’ heart rhythm health through Apple Watch

California has experienced multiple devastating wildfires in 2020 and 2021. Dr. Cheong, who studies the social and health impacts of environmental disasters and climate change, saw an opportunity to study the effects of wildfire smoke on the heart health of individual firefighters.

Through her contacts in the research community, Dr. Cheong learned that the Apple Watch could help her get the health information she needed. She added: “A colleague of mine at Stanford shared his experience with the Apple Watch, which is known for its accurate heart rate. I’ve always wanted to be able to use the sensor to do more non-invasive analysis of individuals and get more accurate heart rates.” health measurement data.”

As many as 200 firefighters will be involved in the study in areas where wildfire season begins in spring in Texas and summer in California. The study plans to monitor heart rate and rhythm, sleep, blood oxygen, activity data, etc. with Apple Watch. Firefighters will also wear air quality monitors and conduct surveys on sleep, activity and symptoms related to wildfire smoke.

“Firefighters will definitely benefit from this research. We know wildfire smoke can directly affect their health, and with a study like this, they will be able to see immediate results.”

“The point of this study is not to prove or disprove a hypothesis,” said Dr. Cheong. “It’s more exploratory, and the results will help us understand the accuracy of this type of analysis to generate tailored interventions. I also think that Research helps us better understand high-risk populations.”

Apple Watch already being used to study atrial fibrillation

According to European epidemiologists, the incidence of atrial fibrillation in the European Union is expected to double by 2060. Atrial fibrillation is a common heart rhythm irregularity that, if left untreated, can have serious effects, such as increasing the risk of stroke or heart failure.

At the University Medical Center Amsterdam, Sebastiaan Blok, MD, Director of Smart Healthcare (eHealth) at the Netherlands Center for Cardiology, and his colleagues are exploring ways to detect atrial fibrillation early. The researchers developed a randomized controlled study as part of a larger initiative called HartWacht, the first smart reimbursable healthcare (eHealth) concept.

In the Netherlands, “approximately 300,000 people are diagnosed with atrial fibrillation. But it is estimated that an additional 100,000 people may not know they have the condition because they are asymptomatic,” said study team member Nicole van Steijn, MD.

The study plans to enroll more than 300 patients over the age of 65 who meet atrial fibrillation risk thresholds. Half of the participants (the intervention group) wore the Apple Watch for at least 12 hours a day.

“The Apple Watch is a widely used and reliable consumer wearable device, and we thought it was a perfect fit for our research to learn more about how we can integrate it into the larger health picture,” said Dr. Blok. in the system.”

The team’s study design expected participants to have an EKG every three weeks or when symptoms began. If participants were notified of an arrhythmia, researchers will contact them, direct them to an EKG and share the results. During the three weeks of the study, the researchers identified one participant in the intervention group who had atrial fibrillation but did not develop any symptoms.

The study is a start to what researchers hope to learn about the Apple Watch. In the future, they plan to explore ways to identify possible opportunities to use an ECG app to monitor patients at home, since certain medications may alter heart rhythms. Given that heart failure is a costly disease, they are also thinking about how to use the Apple Watch to monitor heart failure patients at home and identify predictive biomarkers of disease progression.

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