2023-08-06 16:00:00
Researchers at the Beckman Research Institute in City of Hope, California (one of the largest cancer research and treatment organizations in the United States) believe they have discovered a molecule capable of disrupting cell replication and repair. cancer cell DNA. In other words, a new cancer therapy capable of destroying solid tumors, “effective when used as monotherapy, as well as when used in combination with existing chemotherapies”.
“Orally administrable and metabolically stable, AOH1996 suppresses tumor growth as monotherapy or in combination treatment, but does not cause any noticeable side effects”, underline the researchers, in the journal Cell chemical biology.
Soon a phase 1 trial in humans
In a pre-clinical study, this molecule proved effective once morest cells derived from cancers of the breast, prostate, brain, ovaries, cervix, lungs and skin, on models animals. But a phase 1 clinical trial is underway to test this new chemotherapy in humans.
“Our cancer pill is like a snowstorm shutting down a key airline hub, halting all inbound and outbound flights only on planes carrying cancer cells,” adds study co-author Dr. Linda Malkas.
The study also shows (…)
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