2023-10-19 10:15:59
How to determine the effectiveness of a painkiller? By comparing it with a placebo, of course! It is certain that for moderate to severe acute postoperative pain, a placebo will not have the same effect as a horse painkiller like sufentanil (Dzuveo). The comparison is not fair! And the Prescribe magazine goes further by talking regarding an unethical evaluation. ” The absence of an active comparator in these trials prevents any progress from being demonstrated; it is ethically unacceptable because the patients in the control group received a placebo even though there are effective drugs to relieve pain “, deplores the medical journal. In short, it would have been necessary to compete sufentanil with another painkiller to validate its evaluation. However, this is sufficient for the European Medicines Agency (Ema) which endorses a very broad authorized indication of the opioid. And Prescribe to conclude that Ema ” serves companies, not patients “.
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#Effectiveness #painkillers #dice #loaded
