FDA approves new nasal spray to treat migraine headaches for adults


Written by Amal Allam

Saturday, March 11, 2023 11:18 AM

The US Food and Drug Administration (FDA) has approved a nasal spray as a quick treatment for migraine pain in adults, and the drug company that produces the drug said in a press release that the nasal spray is zavepant Which is the scientific name for the drug, it may relieve pain and symptoms Migraines The other annoying after 15 minutes of use, explaining that the drug is expected to be available in pharmacies in July 2023..

The study found that people who suffer from migraines get less eye movement sleep, and there are actually a number of different types of medications available to treat migraines, including several types of nasal sprays.. According to the network CNN In news, the new spray is the first to work by blocking a peptide associated with the calcitonin gene CGRP It is a protein released in the brain that contributes to inflammation. Many drives block the gene CGRP But many people with migraines experience severe nausea and cannot tolerate the medications they have to take, and it’s also an alternative for people with heart conditions or other conditions that prevent them from safely using other types of migraine treatments..

In two studies where subjects with migraines did not know whether they were receiving medication or a placebo, the spray was more effective in relieving migraine pain within two hours compared to a nasal spray without any active ingredients..

In one of the studies published in the journal The Lancet Neurology About 24% of people who took a single 10-milligram dose of the spray reported feeling no pain after two hours, compared to 15% of the group who got a nasal spray without any active ingredients, a difference that was statistically significant. The main side effect was What was reported in the study was an altered sense of taste, which affected about 1 in 5 people who took the drug. Other side effects were nasal discomfort and nausea..

“When people get a migraine, it has a significant negative impact on their daily life,” said Dr. Kathleen Mullin, associate medical director at the New England Institute of Neurology and Headache who has studied the drug. “Among my migraine patients, one of the most important features of choice is Acute treatment is how quickly it works As a nasal spray with rapid absorption of the drug, the spray offers an alternative treatment option for people who need pain relief or cannot take oral medications because of nausea or vomiting, so they can return to normal function quickly “.

Migraines are estimated to affect more than 10% of people globally, and are 3 times more common in women than in men. They often involve a throbbing headache that can last for hours or days. They may involve sensitivity to light or Voice, nausea, vomiting, or visual disturbances.






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