2023-11-01 05:00:02
A skin patch could well mark the end of painful medical injections. Researchers at the University of Bath have developed a microneedle patch that delivers medication painlessly, eliminating the need for injections or taking medication by mouth. These patches made using hydrogel stand out for their affordable cost, largely thanks to their 3D printing manufacturing, which allows easy customization.
The patch itself is incredibly small, smaller than a one euro coin. It incorporates barely visible microneedles that penetrate the first layers of the skin without pain. organism whose nervous system detects a…). What makes it unique is the fact that the active substance is encapsulated inside the hydrogel structure, not requiring the use of a separate “reservoir”. In addition, its cost is lower than that of patches already available on the market, since it is manufactured using 3D printed molds, which allows easy customization (All inclusive as a set of what exists is often interpreted as the world or…) by keeping costs low. The microneedles, barely visible, painlessly pierce the first layers of the skin. On contact with the liquid (The liquid phase is a state of matter. In this form, the matter is…) under the skin barrier, the microneedles which are hydrophilic swell, making it possible to deliver a specific dose of the drug (A drug is a substance or composition presented as having…) directly in the body.
In experiments carried out at the University of Bath, these patches successfully administered doses of antibiotics provoking a vigorous response against bacteria responsible for serious infections, such as Escherichia Coli (Escherichia coli, also called colibacillus or E. coli, is a bacteria…) or Staphylococcus (Staphylococcus (Louis Pasteur, 1880) is a bacteria of the genus: cocci, gram positive,… .) Aureus. In addition, the patch can also work in reverse (In mathematics, the inverse of an element x of a set provided with a law of…) by extracting small quantities of liquid from under the skin for a medical analysis, which could be particularly useful for monitoring lactate levels and other substances in patients with infections.
The creator of this patch, Dr Hannah Leese, a chemical engineer at the University of Bath, points out that microneedles have undeniable advantages over injections and oral intake. She explains that injections are often perceived as invasive and expensive, in addition to causing fear among people with needle phobia. Additionally, they can introduce pathogens, such as bacteria, that can cause infections. Taking medications orally, although more common, also has disadvantages, such as gastrointestinal side effects and delays in the effectiveness of the medication. The next step in the research will be to further refine the microneedle platform, and conduct studies on animals before moving on to clinical trials on humans. . Researchers hope that these patches can soon be available to the general public, providing a painless and effective solution for drug delivery. This innovative patch could also pave the way for administering vaccines and monitoring hormone levels, opening new perspectives for medicine. …) and health (Health is a state of complete physical, mental and social well-being, and does not consist of…).
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