Grant Awarded to Research Project Exploring Neurovascular Activity and Noradrenergic Modulation

2023-07-19 19:53:25

A research project led by Michèle Desjardins, assistant professor in the Department of Physics, Engineering Physics and Optics, has obtained a grant of $200,000!

This funding, granted over two years, is provided by the New Frontiers in Research Fund Exploration component that supports high-risk, high-reward interdisciplinary research. The project in question entitled “A multimodal imaging platform to quantify noradrenergic modulation of neurovascular activity in vivo” will also be carried out with Vincent Breton-Provencher of the Faculty of Medicine.

Thanks to the interdisciplinary expertise of the team members in physics, optics and neurosciences, certain misunderstood mechanisms of functional brain imaging techniques will be studied. First, the team will design a multimodal imaging platform to record neurovascular activity as well as a fluorescent sensor for norepinephrine dynamics in the cortex. Secondly, the role of norepinephrine in the modulation of neurovascular activity at the level of the cortex will be analyzed.

These results could influence the development of new experimental procedures for functional imaging and provide insights into neurodegenerative diseases involving neurovascular interactions.

Congratulations to the whole team!

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