Heart Health: 5 Key Risk Factors to Prevent Cardiovascular Disease

L’efficienza del muscolo cardiaco si riflette sul funzionamento dell’intero organismo, ed è necessario che sia in buona salute perché funzionino al meglio tutti gli apparati, organi e tessuti. According to a panel discussed by Corriere della Sera, preserving heart function requires targeted control over five primary risk factors: smoking, low-density lipoprotein cholesterol, hypertension, diabetes, and physical inactivity.

In Plain English: The Clinical Takeaway

  • Endocrine System Role: The heart functions as more than a mechanical pump; it is also an endocrine organ that sends signals to the rest of the body and dialogues with other organs.
  • Multiplicative Risk: The five core cardiovascular hazards do not merely add together; their negative physiological impacts multiply when combined.
  • Secondary Prevention Windows: Post-infarct recovery requires immediate therapeutic intervention to stabilize arterial plaques and lower the risk of recurrent cardiac events.

Why the Heart Functions as an Endocrine Organ

Corriere della Sera reported that the heart operates as an endocrine organ sending signals to the rest of the body. During an event hosted by Corriere della Sera titled «La salute del cuore non è “solo” la salute del cuore. Anticipare le mosse per preservarla», specialists detailed how cardiac tissue dialogues with all other organs, from the brain to the kidneys, to sustain overall organismal function.

Furio Colivicchi, director of the Clinical Cardiology and Rehabilitation Unit at San Filippo Neri Hospital in Rome and president of the Fondazione Anmco Per il Tuo Cuore, identified the five primary pathological drivers: tobacco use in any form, low-density lipoprotein (LDL) cholesterol, arterial hypertension, diabetes, and sedentary behavior. Colivicchi emphasized that the effects of these five elements multiply among themselves.

Evaluating Primary Prevention and Lipid Profiles

Adopting healthy habits—not smoking, physical activity, and a balanced diet—can decrease cardiovascular risk by approximately 20 percent, as noted by Leonardo De Luca, director of the Cardiology Unit at Policlinico San Matteo in Pavia and vice president of the Fondazione Anmco Per il Tuo Cuore, in Corriere della Sera reporting. De Luca pointed out that if this risk reduction were a drug, it would be considered excellent.

Among all risk factors, LDL cholesterol has a fundamental role in the appearance of atherosclerosis.

Cardiovascular Risk Factor Clinical Mechanism Primary Therapeutic Target
LDL Cholesterol Fundamental role in the appearance of atherosclerosis Under 55 mg/dl for secondary prevention
Type 2 Diabetes Damages tissues, organs and apparatuses via hyperglycemia Strict glycemic control
Hypertension Increases vascular resistance Systolic pressure below 130 mmHg post-infarct
Tobacco Use Primary risk factor Complete cessation
Sedentary Lifestyle Primary risk factor 30 to 40 minutes of daily walking

Managing the Silent Progression of Type 2 Diabetes

Type 2 diabetes affects approximately 6 percent of the general population. Paolo Fiorina, docente di endocrinologia dell’Università di Milano and responsabile del Dipartimento di Nefrologia e Diabetologia dell’Ospedale Sacco di Milano, explained via Corriere della Sera that it is a silent killer, as it is often diagnosed after a cardiovascular, renal, or ocular event, all direct consequences of hyperglycemia. Chronic glucose excess damages all tissues, organs, and apparatuses.

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Insulin acts as an hormone that regulates glycemic metabolism and directly influences the heart because it regulates the synthesis of cardiac muscle proteins and the production of nitrossido, an anti-atherosclerosis vasodilator.

Secondary Prevention Following Acute Myocardial Events

Patients who have already suffered a myocardial infarction or stroke face a significantly elevated risk profile. De Luca noted in Corriere della Sera that secondary prevention must be initiated immediately during the hospital stay to set up a shared strategy with the patient and favor adherence to therapies. Antiplatelets, antiarrhythmics, and lipid-lowering drugs are essential to stabilize plaques and prevent a recurrence of infarction.

Statistical data cited in Corriere della Sera show that the probability of a secondary vascular event reaches 5 to 10 percent within the first year, escalating to 15 to 20 percent over a five-year horizon. This occurs also because risk factor targets are not reached and many stop taking medications, with Colivicchi noting that 22 percent of those who have had an infarct still smoke.

Expanding Preventive Outreach in Regional Communities

The Cinque Mulini organization scheduled its event titled «Dalla Tavola al Traguardo – Il cuore in salute: stili di vita e nutrizione» for Friday, November 7, 2026, at the Poli Hotel in San Vittore Olona. The initiative addresses everyday nutritional choices, physical activity, and the adoption of correct lifestyles.

Heart Health: 5 Key Risk Factors to Prevent Cardiovascular Disease
Photo: VareseNews

The event follows courses on BLSD by the association Sessantamilavite da Salvare O.d.V. The evening features remarks from Silvia Scurati, Consigliere di Regione Lombardia and Coordinatrice dell’Intergruppo Consiliare “Diabete, Obesità e Stili di Vita”. The program also introduces the YouGoody project, operating under the international Athletics for a Better World framework promoted by World Athletics.

Contraindications & When to Consult a Doctor

For individuals recovering from acute cardiac events, rehabilitation involves maintaining weight in the norm with an adequate diet.

Preventing Progression Toward Cardiac Insufficiency

While demographic shifts have changed the age of a first myocardial infarction—today the average age exceeds 65 years in men and nears 80 in women, per Corriere della Sera—treating older populations presents challenges to avoid cardiac decompensation.

Controlling and Preventing Heart Disease Risk Factors

Colivicchi emphasized in Corriere della Sera reporting that preventing decompensation, which is the arrival point of cardiovascular diseases and the first cause of hospital admission excluding childbirth, is fundamental. It is not only a cause of death, but a cause of a drastic worsening of quality of life.

References

  • Corriere della Sera: Special reporting on cardiovascular health (corriere.it).
  • Cinque Mulini: Public health and nutritional prevention coverage (VareseNews).
  • Fondazione Anmco Per il Tuo Cuore: Clinical guidelines on cardiovascular prevention.
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Priya Deshmukh - Senior Editor, Health

Priya Deshmukh Senior Editor, Health Deshmukh is a practicing physician and renowned medical journalist, honored for her investigative reporting on public health. She is dedicated to delivering accurate, evidence-based coverage on health, wellness, and medical innovations.

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